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Author Junior, Milton Marcio Machota ♦ Maciel, Paulo Roberto ♦ Ogata, Silvio Atsushi ♦ Bleggitorres, Luiz Fernando ♦ Marques, Fabricio Machado ♦ Gentili, Arthur Cornelian
Source Directory of Open Access Journals (DOAJ)
Content type Text
Publisher Sociedade Brasileira de Patologia Clínica
File Format HTM / HTML
Date Created 2013-08-31
Copyright Year ©2012
Language English
Subject Domain (in LCC) RB1-214
Subject Keyword Pathology ♦ Primário ♦ Sarcoma ♦ Sistema nervoso central ♦ Medicine ♦ Primary ♦ Central nervous system
Abstract INTRODUÇÃO: O sarcoma de sistema nervoso central (SNC) é uma neoplasia rara, com incidência de 0,1% a 4,3% dos tumores intracranianos. São tumores agressivos com prognóstico reservado e a maioria é tratada com ressecção radical. RELATO: Homem, 29 anos, com episódios de crises convulsivas e diagnóstico de hemorragia intraparenquimatosa. Durante a cirurgia, foi identificada lesão bem delimitada. A histologia demonstrou neoplasia fusocelular com atipias e numerosas mitoses. Os únicos marcadores imuno-histoquímicos positivos foram vimentina e S-100. O diagnóstico foi de sarcoma indiferenciado de alto grau. CONCLUSÃO: No diagnóstico diferencial de sarcomas de SNC, devem-se excluir lesões metastáticas e gliossarcoma.INTRODUCTION: The central nervous system (CNS) sarcoma is a rare neoplasm with an incidence of 0.1% to 4.3% in intracranial tumors. They are aggressive with poor prognosis, and mostly treated with radical resection. REPORT: 29 year-old male patient with episodes of seizures and diagnosed with intraparenchymal hemorrhage. During the surgery a well-defined lesion was identified. Histology showed a spindle cell neoplasm with atypia and numerous mitoses. The immunohistochemical markers were positive only for vimentin and S-100. The diagnosis was high-grade undifferentiated sarcoma. CONCLUSION: Metastatic lesions and gliosarcoma should be excluded in the differential diagnosis of CNS sarcomas.
ISSN 16762444
Age Range 18 to 22 years ♦ above 22 year
Educational Use Research
Education Level UG and PG ♦ Career/Technical Study
Learning Resource Type Article
Publisher Date 2012-04-01
e-ISSN 16762444
Journal Jornal Brasileiro de Patologia e Medicina Laboratorial
Volume Number 48
Issue Number 2
Page Count 4
Starting Page 135
Ending Page 138


Source: Directory of Open Access Journals (DOAJ)