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Author Ginis, Tayfur ♦ Akcan, Fatih Alper ♦ Capanoglu, Murat ♦ Toyran, Muge ♦ Ersu, Refika ♦ Kocabas, Can Naci ♦ Civelek, Ersoy
Source World Health Organization (WHO)-Global Index Medicus
Content type Text
Publisher Taylor & Francis
File Format HTM / HTML
Language English
Difficulty Level Medium
Subject Domain (in DDC) Technology ♦ Medicine & health ♦ Diseases
Subject Keyword Discipline Pulmonology
Abstract BACKGROUND: The presence of sleep-disordered breathing (SDB) in children with asthma may cause difficult to control asthma. OBJECTIVES: The aim of this study was to determine the frequency of SDB in children with asthma, to evaluate its effects on asthma control and to assess the risk factors associated with the presence of SDB. METHODS: Parents of children who Sleep Questionnaire (PSQ) and the Childhood Asthma Control Test (C-ACT). Asthma control level was assessed according to Global Initiative for Asthma (GINA). Same ear-nose-throat (ENT) specialist evaluated all patients. A 4-point tonsil grading method and adenoid-nasopharynx ratio were used to categorize tonsil and adenoid size, respectively. RESULTS: A total of 408 children (275 male, 67.4%) with a mean age of 8.1 ± 3.2 years were included. Nearly 40% of asthmatic children were not-well-controlled according to GINA and 34.6% of all patients had SDB according to PSQ. Multivariate logistic regression analysis revealed that coexistence of SDB [OR: 6.62, 95% CI (4.21-10.41); p < 0.001)] and tonsillar hypertrophy [OR: 3.47; 95% CI (1.05-11.5); p < 0.041] were independent risk factors for not-well-controlled asthma in asthmatic children after other established contributors to asthma control were adjusted. CONCLUSIONS: Our study showed that SDB is a strong risk factor for not-well-controlled asthma in asthmatic children independent of other confounders. In addition, tonsillar hypertrophy may have a role in the association between SDB and not-well-controlled asthma in childhood.
Description Country affiliation: Turkey
Author Affiliation: Ginis T ( a Department of Pediatric Allergy and Immunology , Ankara Children's Hematology Oncology Training and Research Hospital , Ankara , Turkey.); Akcan FA ( b Department of Ear, Nose and Throat , Ankara Children's Hematology Oncology Training and Research Hospital , Ankara , Turkey.); Capanoglu M ( a Department of Pediatric Allergy and Immunology , Ankara Children's Hematology Oncology Training and Research Hospital , Ankara , Turkey.); Toyran M ( a Department of Pediatric Allergy and Immunology , Ankara Children's Hematology Oncology Training and Research Hospital , Ankara , Turkey.); Ersu R ( c Department of Pediatric Pulmonology Marmara University Faculty of Medicine , Istanbul , Turkey.); Kocabas CN ( d Department of Pediatric Allergy and Immunology , Faculty of Medicine, Mugla Sitki Kocman University , Mugla , Turkey.); Civelek E ( a Department of Pediatric Allergy and Immunology , Ankara Children's Hematology Oncology Training and Research Hospital , Ankara , Turkey.)
ISSN 02770903
Educational Role Student ♦ Teacher
Age Range above 22 year
Educational Use Reading ♦ Research ♦ Self Learning
Interactivity Type Expositive
Education Level UG and PG
Learning Resource Type Article
Publisher Date 2017-01-06
Publisher Place Great Britain (UK)
e-ISSN 15324303
Journal Journal of Asthma


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Source: WHO-Global Index Medicus