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Author Umehara, Ryoji ♦ Miyahara, Hidekazu ♦ Okino, Akitoshi ♦ Harada, Makoto ♦ Okada, Tetsuo
Source J-STAGE
Content type Text
Publisher The Japan Society for Analytical Chemistry
Language English
Abstract Wide-bore capillary hydrodynamic chromatography (W-HDC) resolves analytes on the basis of a difference in the extent of radial diffusion simply by their passage through an empty capillary. The combination of this method with ICP-MS proves efficient for the evaluation of the interaction of metal ions with molecular aggregates. Lecithin vesicles are suitable molecular aggregates for the uptake of the lanthanide ions in the presence of the first row transition metal ions, suggesting that the present method is applicable to the screening of the molecular aggregate system suitable for selective extraction of a particular targeted small molecule. The visual inspection of the elution profiles gives us qualitative but useful information on the interaction between the vesicle and metal ions. In addition, studying the slope of the front edge of an elution curve provides more quantitative implications.
ISSN 09106340
Learning Resource Type Article
Publisher Date 2012-04-10
e-ISSN 13482246
Journal Analytical Sciences(analsci)
Volume Number 28
Issue Number 4
Page Count 1
Starting Page 359
Ending Page 359