Thumbnail
Access Restriction
Open

Author Chen, Zhanguang ♦ Peng, Yurui ♦ Chen, Junhui ♦ Zhang, Taiyu ♦ Liu, Guoliang
Source J-STAGE
Content type Text
Publisher The Japan Society for Analytical Chemistry
Language English
Abstract A method for the determination of ofloxacin (OFL) has been developed, based on the enhancement of resonance light scattering (RLS) of OFL in the presence of alizarin violet 3B (AV3B). Under the experimental conditions, the RLS intensity of AV3B was greatly enhanced by adding OFL. At pH 5.09, the enhancement of the RLS intensity at 439.5 nm was proportional to the concentration of OFL in the range 0.10 − 2.50 μg/ml. The detection limit (3σ) was 0.013 μg/ml. At pH 6.90, the enhancement of the RLS intensity at 405.0 nm was proportional to the concentration of OFL in the range 0.05 − 3.00 μg/ml. The detection limit (3σ) was 0.021 μg/ml. The proposed method with high sensitivity, selectivity and reproducibility was satisfactorily applied to the determination of OFL in human serum.
ISSN 09106340
Learning Resource Type Article
Publisher Date 2009-07-10
e-ISSN 13482246
Journal Analytical Sciences(analsci)
Volume Number 25
Issue Number 7
Page Count 6
Starting Page 891
Ending Page 896


Open content in new tab

   Open content in new tab