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Author Jones, Kevin C. ♦ Solberg, Timothy D. ♦ Avery, Stephen ♦ Vander Stappen, François ♦ Janssens, Guillaume ♦ Prieels, Damien ♦ Bawiec, Christopher R. ♦ Lewin, Peter A. ♦ Sehgal, Chandra M.
Source United States Department of Energy Office of Scientific and Technical Information
Content type Text
Language English
Subject Keyword APPLIED LIFE SCIENCES ♦ ACOUSTIC MEASUREMENTS ♦ AMPLITUDES ♦ ENERGY ABSORPTION ♦ ENERGY LOSSES ♦ FUNCTION GENERATORS ♦ HOSPITALS ♦ IN VIVO ♦ ISOCHRONOUS CYCLOTRONS ♦ PATIENTS ♦ PRESSURE RANGE MEGA PA ♦ PROTON BEAMS ♦ SOUND WAVES ♦ VERIFICATION
Abstract Purpose: To measure the acoustic signal generated by a pulsed proton spill from a hospital-based clinical cyclotron. Methods: An electronic function generator modulated the IBA C230 isochronous cyclotron to create a pulsed proton beam. The acoustic emissions generated by the proton beam were measured in water using a hydrophone. The acoustic measurements were repeated with increasing proton current and increasing distance between detector and beam. Results: The cyclotron generated proton spills with rise times of 18 μs and a maximum measured instantaneous proton current of 790 nA. Acoustic emissions generated by the proton energy deposition were measured to be on the order of mPa. The origin of the acoustic wave was identified as the proton beam based on the correlation between acoustic emission arrival time and distance between the hydrophone and proton beam. The acoustic frequency spectrum peaked at 10 kHz, and the acoustic pressure amplitude increased monotonically with increasing proton current. Conclusions: The authors report the first observation of acoustic emissions generated by a proton beam from a hospital-based clinical cyclotron. When modulated by an electronic function generator, the cyclotron is capable of creating proton spills with fast rise times (18 μs) and high instantaneous currents (790 nA). Measurements of the proton-generated acoustic emissions in a clinical setting may provide a method for in vivo proton range verification and patient monitoring.
ISSN 00942405
Educational Use Research
Learning Resource Type Article
Publisher Date 2015-12-15
Publisher Place United States
Journal Medical Physics
Volume Number 42
Issue Number 12