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Author Minns, Alicia B. ♦ McIlvoy, Anesia ♦ Clark, Alycia ♦ Clark, Richard F. ♦ Cantrell, F. Lee
Source World Health Organization (WHO)-Global Index Medicus
Content type Text
Publisher Elsevier
File Format HTM / HTML
Language English
Difficulty Level Medium
Subject Domain (in DDC) Social sciences ♦ Social problems & services; associations ♦ Social welfare problems & services ♦ Natural sciences & mathematics ♦ Chemistry & allied sciences ♦ Life sciences; biology ♦ Biochemistry ♦ Natural history of organisms ♦ Technology ♦ Medicine & health ♦ Pharmacology and therapeutics ♦ Diseases ♦ Manufacture for specific uses ♦ Precision instruments & other devices
Subject Domain (in MeSH) Eukaryota ♦ Organisms ♦ Organic Chemicals ♦ Chemical Actions and Uses ♦ Chemicals and Drugs ♦ Investigative Techniques ♦ Analytical, Diagnostic and Therapeutic Techniques and Equipment ♦ Persons ♦ Persons ♦ Health Care Facilities, Manpower, and Services ♦ Health Care ♦ Geographic Locations ♦ Geographic Locations
Subject Keyword Discipline Emergency ♦ Discipline Medicine ♦ Acetates ♦ Adverse Effects ♦ Methanol ♦ Poisoning ♦ Adolescent ♦ California ♦ Epidemiology ♦ Child ♦ Child, Preschool ♦ Female ♦ Humans ♦ Infant ♦ Male ♦ Poison Control Centers ♦ Retrospective Studies ♦ Solvents ♦ Young Adult ♦ Journal Article
Abstract OBJECTIVES: This retrospective study aims to review California Poison Control System data to qualitatively describe reported methyl acetate (MA) exposures and determine if a metabolic acidosis develops. METHODS: We queried the Poison Control System data between January 1997 and December 1, 2010. Inclusion criteria were single MA ingestions. RESULTS: Eighty-three cases were analyzed. Females made up 52% of study subjects. Seventy-five cases (90%) were 5 years or younger. Most (93%) ingestions were unintentional. Sixty-two cases (75%) were referred to a health care facility (HCF). Of these, 75% of cases referred to an HCF had no effect, and 25% of cases had a minor effect. There were no major effects, including deaths reported. One case received single-dose activated charcoal, and 1 case received intravenous fluids as therapy. All other cases were observed only. Of all cases, including home-managed and HCF cases, 63 (76%) had no symptoms. Vomiting was observed in 12 cases (14%), drowsiness in 1 case, ataxia in 1 case, abdominal pain in 1 case, and throat/oral irritation in 5 cases. Fifty-three percent of cases referred to HCF had at least 1 chemistry panel done (27% had >1 chemistry panel done). One patient had a mild metabolic acidosis without symptoms that resolved after a period of observation. There was no renal dysfunction. CONCLUSION: These data suggest that minor ingestions of MA may be observed at home, but a prospective study is needed to exclude the risk of home observation.
Spatial Coverage California
Description Country affiliation: United States
Author Affiliation: Minns AB ( Department of Emergency Medicine, Division of Medical Toxicology, University of California, San Diego, CA 92103-8925, USA. abminns01@yahoo.com)
ISSN 07356757
Educational Role Student ♦ Teacher
Age Range above 22 year
Educational Use Reading ♦ Research ♦ Self Learning
Interactivity Type Expositive
Education Level UG and PG
Learning Resource Type Article
Publisher Date 2013-06-01
Publisher Place United States
e-ISSN 15328171
Journal The American Journal of Emergency Medicine
Volume Number 31
Issue Number 6


Source: WHO-Global Index Medicus