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Author Zhao, J. ♦ Last, R. L.
Source World Health Organization (WHO)-Global Index Medicus
Content type Text
Publisher American Society of Plant Biologists
File Format HTM / HTML
Language English
Difficulty Level Medium
Subject Domain (in DDC) Natural sciences & mathematics ♦ Chemistry & allied sciences ♦ Life sciences; biology ♦ Physiology & related subjects ♦ Biochemistry ♦ Natural history of organisms ♦ Microorganisms, fungi & algae ♦ Technology ♦ Medicine & health ♦ Human physiology ♦ Pharmacology and therapeutics
Subject Domain (in MeSH) Eukaryota ♦ Bacteria ♦ Viruses ♦ Organisms ♦ Organic Chemicals ♦ Heterocyclic Compounds ♦ Amino Acids, Peptides, and Proteins ♦ Nucleic Acids, Nucleotides, and Nucleosides ♦ Complex Mixtures ♦ Chemicals and Drugs ♦ Chemical Phenomena ♦ Plant Physiological Phenomena ♦ Biological Sciences
Subject Keyword Discipline Botany ♦ Arabidopsis ♦ Metabolism ♦ Indoles ♦ Plant Extracts ♦ Plant Proteins ♦ Thiazoles ♦ Tryptophan ♦ Biosynthesis ♦ Microbiology ♦ Virology ♦ Caulimovirus ♦ Isolation & Purification ♦ Mosaic Viruses ♦ Plant Diseases ♦ Pseudomonas ♦ Rna, Messenger ♦ Sesquiterpenes ♦ Terpenes ♦ Transcription, Genetic ♦ Xanthomonas Campestris ♦ Journal Article ♦ Research Support, U.s. Gov't, Non-p.h.s. ♦ Research Support, U.s. Gov't, P.h.s.
Abstract Little is known about the mechanisms that couple regulation of secondary metabolic pathways to the synthesis of primary metabolic precursors. Camalexin, an indolic secondary metabolite, appears to be the major phytoalexin in Arabidopsis. It was previously shown that camalexin accumulation is caused by infection with plant pathogens, by abiotic elicitors, and in spontaneous lesions in the accelerated cell death mutant acd2. We demonstrate that the accumulation of this phytoalexin is accompanied by the induction of the mRNAs and proteins for all of the tryptophan biosynthetic enzymes tested. A strong correlation was observed between the magnitude of camalexin accumulation and the induction of tryptophan biosynthetic proteins, indicating coordinate regulation of these processes. Production of disease symptoms is not sufficient for the response because systemic infection with cauliflower mosaic virus or cucumber mosaic virus did not induce the tryptophan pathway enzymes or camalexin accumulation. Salicylic acid appears to be required, but unlike other documented pathogenesis-related proteins, it is not sufficient for the coordinate induction. Results with trp mutants suggest that the tryptophan pathway is not rate limiting for camalexin accumulation. Taken together, these results are consistent with the hypothesis that the regulation of the tryptophan pathway in plants responds to needs for biosynthesis of secondary metabolites.
Description Country affiliation: United States
Author Affiliation: Zhao J ( Boyce Thompson Institute for Plant Research, Cornell University, Ithaca, New York 14853-1801, USA.)
ISSN 10404651
Educational Role Student ♦ Teacher
Age Range above 22 year
Educational Use Reading ♦ Research ♦ Self Learning
Interactivity Type Expositive
Education Level UG and PG
Learning Resource Type Article
Publisher Date 1996-12-01
Publisher Place United States
e-ISSN 1531298X
Journal THE PLANT CELL ONLINE
Volume Number 8
Issue Number 12


Source: WHO-Global Index Medicus