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Author Chen, Wenqiong ♦ Provart, Nicholas J. ♦ Glazebrook, Jane ♦ Katagiri, Fumiaki ♦ Chang, Hur-Song ♦ Eulgem, Thomas ♦ Mauch, Felix ♦ Luan, Sheng ♦ Zou, Guangzhou ♦ Whitham, Steve A. ♦ Budworth, Paul R. ♦ Tao, Yi ♦ Xie, Zhiyi ♦ Chen, Xi ♦ Lam, Steve ♦ Kreps, Joel A. ♦ Harper, Jeffery F. ♦ Si-Ammour, Azzedine ♦ Mauch-Mani, Brigitte ♦ Heinlein, Manfred ♦ Kobayashi, Kappei ♦ Hohn, Thomas ♦ Dangl, Jeffery L. ♦ Wang, Xun ♦ Zhu, Tong
Source World Health Organization (WHO)-Global Index Medicus
Content type Text
Publisher American Society of Plant Biologists
File Format HTM / HTML
Language English
Difficulty Level Medium
Subject Domain (in DDC) Natural sciences & mathematics ♦ Chemistry & allied sciences ♦ Life sciences; biology ♦ Physiology & related subjects ♦ Biochemistry ♦ Genetics and evolution ♦ Natural history of organisms ♦ Microorganisms, fungi & algae ♦ Technology ♦ Medicine & health ♦ Human anatomy, cytology, histology ♦ Human physiology ♦ Pharmacology and therapeutics ♦ Diseases ♦ Manufacture for specific uses ♦ Precision instruments & other devices
Subject Domain (in MeSH) Plant Structures ♦ Anatomy ♦ Eukaryota ♦ Bacteria ♦ Organisms ♦ Organic Chemicals ♦ Lipids ♦ Amino Acids, Peptides, and Proteins ♦ Nucleic Acids, Nucleotides, and Nucleosides ♦ Chemicals and Drugs ♦ Investigative Techniques ♦ Analytical, Diagnostic and Therapeutic Techniques and Equipment ♦ Physical Phenomena ♦ Chemical Phenomena ♦ Genetic Phenomena ♦ Biological Sciences
Subject Keyword Discipline Botany ♦ Arabidopsis ♦ Genetics ♦ Gene Expression Profiling ♦ Transcription Factors ♦ Growth & Development ♦ Microbiology ♦ Bacteria ♦ Pathogenicity ♦ Cold Temperature ♦ Conserved Sequence ♦ Cyclopentanes ♦ Metabolism ♦ Ethylenes ♦ Gene Expression Regulation, Plant ♦ Multigene Family ♦ Oligonucleotide Array Sequence Analysis ♦ Methods ♦ Oxylipins ♦ Phylogeny ♦ Plant Roots ♦ Plants, Genetically Modified ♦ Rna, Plant ♦ Salicylic Acid ♦ Signal Transduction ♦ Journal Article ♦ Research Support, Non-u.s. Gov't
Abstract Numerous studies have shown that transcription factors are important in regulating plant responses to environmental stress. However, specific functions for most of the genes encoding transcription factors are unclear. In this study, we used mRNA profiles generated from microarray experiments to deduce the functions of genes encoding known and putative Arabidopsis transcription factors. The mRNA levels of 402 distinct transcription factor genes were examined at different developmental stages and under various stress conditions. Transcription factors potentially controlling downstream gene expression in stress signal transduction pathways were identified by observed activation and repression of the genes after certain stress treatments. The mRNA levels of a number of previously characterized transcription factor genes were changed significantly in connection with other regulatory pathways, suggesting their multifunctional nature. The expression of 74 transcription factor genes responsive to bacterial pathogen infection was reduced or abolished in mutants that have defects in salicylic acid, jasmonic acid, or ethylene signaling. This observation indicates that the regulation of these genes is mediated at least partly by these plant hormones and suggests that the transcription factor genes are involved in the regulation of additional downstream responses mediated by these hormones. Among the 43 transcription factor genes that are induced during senescence, 28 of them also are induced by stress treatment, suggesting extensive overlap responses to these stresses. Statistical analysis of the promoter regions of the genes responsive to cold stress indicated unambiguous enrichment of known conserved transcription factor binding sites for the responses. A highly conserved novel promoter motif was identified in genes responding to a broad set of pathogen infection treatments. This observation strongly suggests that the corresponding transcription factors play general and crucial roles in the coordinated regulation of these specific regulons. Although further validation is needed, these correlative results provide a vast amount of information that can guide hypothesis-driven research to elucidate the molecular mechanisms involved in transcriptional regulation and signaling networks in plants.
Description Country affiliation: United States
Author Affiliation: Chen W ( Torrey Mesa Research Institute, Syngenta Research and Technology, 3115 Merryfield Row, San Diego, California 92121, USA.)
ISSN 10404651
Educational Role Student ♦ Teacher
Age Range above 22 year
Educational Use Reading ♦ Research ♦ Self Learning
Interactivity Type Expositive
Education Level UG and PG
Learning Resource Type Article
Publisher Date 2002-03-01
Publisher Place United States
e-ISSN 1531298X
Journal THE PLANT CELL ONLINE
Volume Number 14
Issue Number 3


Source: WHO-Global Index Medicus