|Source||United States Department of Energy Office of Scientific and Technical Information|
|Subject Keyword||BIOLOGY AND MEDICINE ♦ ANIMAL CELLS ♦ BIOCHEMISTRY ♦ BONE MARROW ♦ DNA ♦ LETHAL DOSE ♦ MICE ♦ NUCLEIC ACIDS ♦ ORGANIC NITROGEN COMPOUNDS ♦ THYMIDINE ♦ TRACER TECHNIQUES ♦ TRITIUM ♦ TUMORS ♦ X RADIATION|
|Abstract||Following large doses of x radiation, death of a murine ascites lymphoma cell occurred by a rapid intermitotic mechanism. The desoxyribonucleic acid (DNA) of these cells was labeled with tritiated thymidine, the cells killed by x- irradiation, and injected intravenously into recipient mice with growing ascites tumors. Tritium appeared in the DNA of the tumor and bone marrow cells of the recipient mice, with all the radioactivity present as thymine. This indicated a salvage and conservation mechanism for these molecules. (M.C.G.)|
|Learning Resource Type||Article|
|Publisher Department||Stanford Univ., Palo Alto, Calif.|
|Organization||Stanford Univ., Palo Alto, Calif.|
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