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Author Mis, J. R. A. ♦ Pierce, M. K. ♦ Kohalmi, S. E. ♦ Kunz, B. A.
Source United States Department of Energy Office of Scientific and Technical Information
Content type Text
Language English
Subject Keyword BASIC BIOLOGICAL SCIENCES ♦ MUTAGENESIS ♦ BIOLOGICAL PATHWAYS ♦ SACCHAROMYCES CEREVISIAE ♦ CHROMOSOMAL ABERRATIONS ♦ DNA SEQUENCING ♦ GENETIC MAPPING ♦ MUTATIONS ♦ TRANSPOSONS ♦ FUNGI ♦ MAPPING ♦ MICROORGANISMS ♦ PLANTS ♦ SACCHAROMYCES ♦ STRUCTURAL CHEMICAL ANALYSIS ♦ YEASTS ♦ Genetics ♦ Microbiology
Abstract A collection of 196 spontaneous mutations in the SUP4-o gene of the yeast Saccharomyces cerevisiae was analyzed by DNA sequencing. The classes of mutation identified included all possible types of base-pair substitution, deletions of various lengths, complex alterations involving multiple changes, and insertions of transposable elements. The authors' findings demonstrate that at least several different mechanisms are responsible for spontaneous mutangenesis in S. cerevisiae.
Educational Use Research
Learning Resource Type Article
Publisher Date 1988-02-01
Publisher Place United States
Journal Mol. Cell. Biol.
Volume Number 8
Issue Number 2
Organization Cellular and Genetic Toxicology Branch, National Institute of Environmental Health Sciences, Research Triangle Park, NC 27709 (US)


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