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Author Zeng, Yan-Bo ♦ Li, Shan-Shan ♦ Mei, Wen-Li ♦ Dong, Wen-Hua ♦ Li, Kai-Mian ♦ Dai, Hao-Fu
Source World Health Organization (WHO)-Global Index Medicus
Content type Text
Publisher Taylor & Francis
File Format HTM / HTML
Language English
Difficulty Level Medium
Subject Domain (in DDC) Natural sciences & mathematics ♦ Chemistry & allied sciences ♦ Life sciences; biology ♦ Physiology & related subjects ♦ Biochemistry ♦ Natural history of organisms ♦ Microorganisms, fungi & algae ♦ Technology ♦ Medicine & health ♦ Human anatomy, cytology, histology ♦ Human physiology ♦ Pharmacology and therapeutics
Subject Domain (in MeSH) Plant Structures ♦ Anatomy ♦ Eukaryota ♦ Bacteria ♦ Organisms ♦ Organic Chemicals ♦ Chemical Actions and Uses ♦ Chemicals and Drugs ♦ Microbiological Phenomena ♦ Biological Sciences
Subject Keyword Discipline Chemistry ♦ Discipline Pharmacology ♦ Anti-bacterial Agents ♦ Isolation & Purification ♦ Diterpenes ♦ Manihot ♦ Chemistry ♦ Pharmacology ♦ Methicillin Resistance ♦ Drug Effects ♦ Methicillin-resistant Staphylococcus Aureus ♦ Plant Stems ♦ Sesquiterpenes ♦ Journal Article ♦ Research Support, Non-u.s. Gov't
Abstract A new eremophilane sesquiterpene, sporogen AO-2 (1), and a new beyerane diterpene, thecacorin C (2), together with two known compounds, longifoamide-B (3) and methylcholestane-3ß,5 ,6ß-triol (4), were isolated from the stems of Manihot esculenta. The structures of the two new compounds were determined by spectroscopic techniques (UV, IR, MS, 1D, and 2D NMR). Antimicrobial assay showed that compound 3 possessed modest inhibitory effects on Saphylococcus aureus and methicillin-resistant S.aureus, diameters of inhibition zones of which were 7.5 and 8.0 mm, respectively. Compound 4 possessed modest inhibitory effect on S. aureus, the diameter of inhibition zone of which was 6.8 mm.
Description Country affiliation: China
Author Affiliation: Zeng YB ( a Key Laboratory of Biology and Genetic Resources of Tropical Crops, Ministry of Agriculture, Institute of Tropical Bioscience and Biotechnology, Chinese Academy of Tropical Agricultural Sciences , Haikou 571101 , China.)
ISSN 10286020
Educational Role Student ♦ Teacher
Age Range above 22 year
Educational Use Reading ♦ Research ♦ Self Learning
Interactivity Type Expositive
Education Level UG and PG
Learning Resource Type Article
Publisher Date 2015-01-01
Publisher Place Great Britain (UK)
e-ISSN 14772213
Journal Journal of Asian Natural Products Research
Volume Number 17
Issue Number 3


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Source: WHO-Global Index Medicus