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Author Zhou, Yazhou ♦ Yang, Juan ♦ He, Tingting ♦ Shi, Haifeng ♦ Cheng, Xiaonong ♦ Lu, Yuxin
Source World Health Organization (WHO)-Global Index Medicus
Content type Text
Publisher Wiley-VCH
File Format HTM / HTML
Language English
Difficulty Level Medium
Subject Domain (in DDC) Natural sciences & mathematics ♦ Chemistry & allied sciences ♦ Life sciences; biology ♦ Physiology & related subjects ♦ Biochemistry ♦ Natural history of organisms ♦ Microorganisms, fungi & algae ♦ Technology ♦ Medicine & health ♦ Human physiology ♦ Pharmacology and therapeutics ♦ Diseases ♦ Agriculture & related technologies ♦ Manufacture for specific uses ♦ Precision instruments & other devices
Subject Domain (in MeSH) Bacteria ♦ Organisms ♦ Inorganic Chemicals ♦ Chemical Actions and Uses ♦ Chemicals and Drugs ♦ Diagnosis ♦ Investigative Techniques ♦ Analytical, Diagnostic and Therapeutic Techniques and Equipment ♦ Physical Phenomena ♦ Chemical Phenomena ♦ Biological Sciences ♦ Natural Science Disciplines ♦ Physical Sciences ♦ Technology, Industry, and Agriculture ♦ Technology and Food and Beverages
Subject Keyword Discipline Nanotechnology ♦ Anti-infective Agents ♦ Pharmacology ♦ Graphite ♦ Chemistry ♦ Metal Nanoparticles ♦ Nanotechnology ♦ Methods ♦ Silver ♦ Escherichia Coli ♦ Drug Effects ♦ Growth & Development ♦ Ultrastructure ♦ Hydrogen-ion Concentration ♦ Microbial Sensitivity Tests ♦ Photoelectron Spectroscopy ♦ Spectrophotometry, Ultraviolet ♦ Thermodynamics ♦ Time Factors ♦ X-ray Diffraction ♦ Journal Article ♦ Research Support, Non-u.s. Gov't
Abstract A simple and low-energy-consuming approach to synthesize highly stable and dispersive silver nanoparticle–graphene (AgNP–GE) nanocomposites has been developed, in which the stability and dispersivity of the composites are varied greatly with the pH value and temperature of the reaction. The results demonstrate that the optimal reaction conditions are pH 11 at room temperature for 70 min. As-synthesized composites display excellent antimicrobial activity, and can completely inhibit the growth of Escherichia coli cells at a concentration of 20 mg $L^{−1}$ (20 ppm). After treatment with 10 ppm AgNP–GE composites, the cells are killed completely within 3 h. The unique structure imparts such good antimicrobial properties to the composites. Firstly, the sheetlike AgNP–GE tends to be adsorbed and accumulated onto the surface of cells, which can change the permeability and enhance the antimicrobial activity. Secondly, $Ag^{+}$ released from AgNPs can act on the cells effectively and fully, thereby resulting in cell death.
Description Author Affiliation: Zhou Y ( School of Materials Science and Engineering, Jiangsu University, Zhenjiang 212013, PR China.)
ISSN 16136810
Educational Role Student ♦ Teacher
Age Range above 22 year
Educational Use Reading ♦ Research ♦ Self Learning
Interactivity Type Expositive
Education Level UG and PG
Learning Resource Type Article
Publisher Date 2013-10-25
Publisher Place Germany
e-ISSN 16136829
Journal Small
Volume Number 9
Issue Number 20


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Source: WHO-Global Index Medicus