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Author Ivnitski, Dmitri ♦ Artyushkova, Kateryna ♦ Rincón, Rosalba A. ♦ Atanassov, Plamen ♦ Luckarift, Heather R. ♦ Johnson, Glenn R.
Source World Health Organization (WHO)-Global Index Medicus
Content type Text
Publisher Wiley-VCH
File Format HTM / HTML
Language English
Difficulty Level Medium
Subject Domain (in DDC) Natural sciences & mathematics ♦ Chemistry & allied sciences ♦ Life sciences; biology ♦ Physiology & related subjects ♦ Biochemistry ♦ Technology ♦ Medicine & health ♦ Human physiology ♦ Pharmacology and therapeutics ♦ Diseases ♦ Manufacture for specific uses ♦ Precision instruments & other devices
Subject Domain (in MeSH) Inorganic Chemicals ♦ Enzymes and Coenzymes ♦ Chemicals and Drugs ♦ Diagnosis ♦ Investigative Techniques ♦ Analytical, Diagnostic and Therapeutic Techniques and Equipment ♦ Physical Phenomena ♦ Chemical Phenomena ♦ Biological Sciences
Subject Keyword Discipline Nanotechnology ♦ Enzymes, Immobilized ♦ Metabolism ♦ Glucose Oxidase ♦ Nanotubes, Carbon ♦ Silicon Dioxide ♦ Electron Transport ♦ Hydrogen-ion Concentration ♦ Microscopy, Electron, Scanning ♦ Spectrum Analysis ♦ X-rays ♦ Journal Article
Abstract This work demonstrates a new approach for building bioinorganic interfaces by integrating biologically derived silica with single-walled carbon nanotubes to create a conductive matrix for immobilization of enzymes. Such a strategy not only allows simple integration into biodevices but presents an opportunity to intimately interface an enzyme and manifest direct electron transfer features. Biologically synthesized silica/carbon nanotube/enzyme composites are evaluated electrochemically and characterized by means of X-ray photoelectron spectroscopy. Voltammetry of the composites displayed stable oxidation and reduction peaks at an optimal potential close to that of the FAD/FADH(2) cofactor of immobilized glucose oxidase. The immobilized enzyme is stable for a period of one month and retains catalytic activity for the oxidation of glucose. It is demonstrated that the resulting composite can be successfully integrated into functional bioelectrodes for biosensor and biofuel cell applications.
Description Country affiliation: United States
Author Affiliation: Ivnitski D ( Chemical and Nuclear Engineering Department, University of New Mexico, Albuquerque, NM 87131, USA.)
ISSN 16136810
Educational Role Student ♦ Teacher
Age Range above 22 year
Educational Use Reading ♦ Research ♦ Self Learning
Interactivity Type Expositive
Education Level UG and PG
Learning Resource Type Article
Publisher Date 2008-03-01
Publisher Place Germany
e-ISSN 16136829
Journal Small
Volume Number 4
Issue Number 3


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Source: WHO-Global Index Medicus