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Author Shin, Seung Won ♦ Park, Kyung Soo ♦ Shin, Woo Jung ♦ Um, Soong Ho
Source World Health Organization (WHO)-Global Index Medicus
Content type Text
Publisher Wiley-VCH
File Format HTM / HTML
Language English
Difficulty Level Medium
Subject Domain (in DDC) Natural sciences & mathematics ♦ Chemistry & allied sciences ♦ Life sciences; biology ♦ Physiology & related subjects ♦ Biochemistry ♦ Genetics and evolution ♦ Technology ♦ Medicine & health ♦ Human anatomy, cytology, histology ♦ Human physiology ♦ Pharmacology and therapeutics ♦ Agriculture & related technologies
Subject Domain (in MeSH) Cells ♦ Anatomy ♦ Enzymes and Coenzymes ♦ Nucleic Acids, Nucleotides, and Nucleosides ♦ Biomedical and Dental Materials ♦ Chemicals and Drugs ♦ Genetic Phenomena ♦ Biological Sciences ♦ Technology, Industry, and Agriculture ♦ Technology and Food and Beverages
Subject Keyword Discipline Nanotechnology ♦ Artificial Cells ♦ Chemistry ♦ Cell Nucleus ♦ Dna Ligases ♦ Liposomes ♦ Micrornas ♦ Chemical Synthesis ♦ Plasmids ♦ Journal Article ♦ Research Support, Non-u.s. Gov't
Abstract A pseudo-eukaryotic nucleus (PEN) system consisting of a gene-containing DNA hydrogel encapsulated in a liposome is fabricated. Owing to the structural characteristics of gene-containing DNA hydrogel, mRNA transcription efficiency is promoted 2.57-fold. Through the use of PEN as a platform for mRNA delivery to the cytosol, prolonged protein translation is achieved.
Description Author Affiliation: Shin SW ( School of Chemical Engineering, Sungkyunkwan University, Suwon, 440-746, Republic of Korea.); Park KS ( School of Chemical Engineering, Sungkyunkwan University, Suwon, 440-746, Republic of Korea.); Shin WJ ( School of Chemical Engineering, Sungkyunkwan University, Suwon, 440-746, Republic of Korea.); Um SH ( School of Chemical Engineering, Sungkyunkwan University, Suwon, 440-746, Republic of Korea.)
ISSN 16136810
Educational Role Student ♦ Teacher
Age Range above 22 year
Educational Use Reading ♦ Research ♦ Self Learning
Interactivity Type Expositive
Education Level UG and PG
Learning Resource Type Article
Publisher Date 2015-11-04
Publisher Place Germany
e-ISSN 16136829
Journal Small
Volume Number 11
Issue Number 41


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Source: WHO-Global Index Medicus