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Author Richardson, K. ♦ Jevons, S. ♦ Moore, J. W. ♦ Ross, B. C. ♦ Wright, J. R.
Source J-STAGE
Content type Text
Publisher JAPAN ANTIBIOTICS RESEARCH ASSOCIATION
Language English
Abstract Four 1-N-aminohydroxy-alkyl derivatives of kanamycin A were prepared and their in vitro activities against aminoglycoside-sensitive and aminoglycoside-resistant organisms were compared with amikacin. 1-N-[(S)-4-Amino-2-hydroxybutyl] kanamycin A (Fig. 1, compound 2, code no. UK-18, 892) was equipotent to amikacin in all these tests and in mouse protection studies.
ISSN 00218820
Learning Resource Type Article
Publisher Date 1977-01-01
e-ISSN 18811469
Journal The Journal of Antibiotics(antibiotics1968)
Volume Number 30
Issue Number 10
Page Count 4
Starting Page 843
Ending Page 846


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