Thumbnail
Access Restriction
Open

Author Anke, T. ♦ Oberwinkler, F. ♦ Steglich, W. ♦ Schramm, G.
Source J-STAGE
Content type Text
Publisher JAPAN ANTIBIOTICS RESEARCH ASSOCIATION
Language English
Abstract The strobilurins are two antifungal antibiotics which were isolated from the mycelium of Strobilurus tenacellus strain No. 21602. The strobilurins A and B are highly active against yeasts and filamentous fungi. In vitro antitumor activity was tested using cells of the ascitic form of EHRLICH carcinoma. The strobilurins strongly inhibited the incorporation of radioactive leucine, uridine, and thymidine into the acid-insoluble fraction of cells (protein, RNA, and DNA). The molecular formulas as determined by high resolution mass spectrometry are $C_{16}H_{18}O_{3}$ for strobilurin A and $C_{17}H_{19}ClO_{4}$ for strobilurin B.
ISSN 00218820
Learning Resource Type Article
Publisher Date 1977-01-01
e-ISSN 18811469
Journal The Journal of Antibiotics(antibiotics1968)
Volume Number 30
Issue Number 10
Page Count 5
Starting Page 806
Ending Page 810


Open content in new tab

   Open content in new tab