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Author Auer, Herbert ♦ Vander Möse, Angelika ♦ Picher, Otto ♦ Walochnik, Julia ♦ Aspöck, Horst
Source SpringerLink
Content type Text
Publisher Springer-Verlag
File Format PDF
Copyright Year ©2000
Language English
Subject Domain (in DDC) Social sciences ♦ Sociology & anthropology
Abstract For evaluation of the medical relevance of a Toxoplasma IgG avidity test within the Austrian program for screening of pregnant women, 23 sera from women with seroconversions (group 1) and with proven latent Toxoplasma infections (group 3), respectively, as well as 92 sera from women suspected of having a primary infection (group 2) were tested by the indirect immunofluorescence test (IFAT), Sabin-Feldman's dye test (SFT), IgM enzyme-linked immunofluorescence assay (ELFA-IgM), IgA microparticle enzyme immunoassay, and the IgG avidity test. Group 1 sera (seroconversions) revealed a median avidity index (AI) of 0.25, whereas the median AI of group 3 sera (latent infections) was 0.66. In 31 (33.7%) of 92 cases suspected of involving a primary Toxoplasma infection, low (<0.41) or borderline AIs (0.41–0.50) were assessed, and in 61 cases (66.3%) the AIs exceeded 0.50. Finally, a recent infection could be excluded due to the results of the IgG avidity test in 59 cases; in at least 34 IgM-positive cases an unnecessary and, thus, unjustified treatment could be avoided.
ISSN 09320113
Age Range 18 to 22 years ♦ above 22 year
Educational Use Research
Education Level UG and PG
Learning Resource Type Article
Publisher Date 2000-11-20
Publisher Place Berlin/Heidelberg
e-ISSN 14321955
Journal Parasitology Research
Volume Number 86
Issue Number 12
Page Count 6
Starting Page 965
Ending Page 970


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Source: SpringerLink