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Author Place, Nicolas ♦ Yamada, Takashi ♦ Bruton, Joseph D. ♦ Westerblad, Håkan
Source SpringerLink
Content type Text
Publisher Springer-Verlag
File Format PDF
Copyright Year ©2010
Language English
Subject Domain (in DDC) Technology ♦ Medicine & health
Subject Keyword Muscle fatigue ♦ Human ♦ Evoked force ♦ Electromyography ♦ Single muscle fibre ♦ Ca2+ handling ♦ Myofibrillar function ♦ Sports Medicine ♦ Occupational Medicine/Industrial Medicine ♦ Human Physiology
Abstract Prolonged dynamic exercise and sustained isometric contractions induce muscle fatigue, as manifested by decreased performance and a reduction in the maximum voluntary contraction force. Studies with non-invasive measurements in exercising humans show that mechanisms located beyond the sarcolemma are important in the fatigue process. In this review, we describe probable cellular mechanisms underlying fatigue-induced changes in excitation–contraction (E–C) coupling occurring in human muscle fibres during strenuous exercise. We use fatigue-induced changes observed in intact single muscle fibres, where force and cellular Ca2+ handling can be directly measured, to explain changes in E–C coupling observed in human muscle during exercise.
ISSN 14396319
Age Range 18 to 22 years ♦ above 22 year
Educational Use Research
Education Level UG and PG
Learning Resource Type Article
Publisher Date 2010-04-24
Publisher Place Berlin/Heidelberg
e-ISSN 14396327
Journal European Journal of Applied Physiology
Volume Number 110
Issue Number 1
Page Count 15
Starting Page 1
Ending Page 15

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Source: SpringerLink