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Author Fakhar, Mahdi ♦ Asgari, Qasem ♦ Motazedian, Mohammad Hossein ♦ Monabati, Ahmad
Source SpringerLink
Content type Text
Publisher Springer-Verlag
File Format PDF
Copyright Year ©2008
Language English
Subject Domain (in DDC) Technology ♦ Medicine & health
Subject Keyword Immunology ♦ Microbiology ♦ Medical Microbiology
Abstract We report a case of Mediterranean visceral leishmaniasis (MVL) associated with acute lymphoblastic leukemia (ALL) from the South of Iran. The patient, a 12-year-old girl, was known to be a case of ALL and had bone pain and prolonged fever on referral. A trephine biopsy revealed a hypocellular marrow with many amastigotes. Moreover, by specific polymerase chain reaction (PCR) on peripheral blood, a 145 bp band corresponding to kDNA from the genus Leishmania was detected and the species was identified as Leishmania infantum using nested PCR. The patient was treated successfully with two courses of amphotericin B plus IFN-γ. To our knowledge this is first report of MVL/ALL from Iran and possibly the world.
ISSN 09320113
Age Range 18 to 22 years ♦ above 22 year
Educational Use Research
Education Level UG and PG
Learning Resource Type Article
Publisher Date 2008-05-08
Publisher Place Berlin/Heidelberg
e-ISSN 14321955
Journal Parasitology Research
Volume Number 103
Issue Number 2
Page Count 3
Starting Page 473
Ending Page 475

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Source: SpringerLink