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Author Vogelstein, R. Jacob ♦ Tere, Francesco ♦ Etienne Cummings, Ralph ♦ Lewis, M. Anthony ♦ Cohen, Avis H.
Source SpringerLink
Content type Text
Publisher Springer-Verlag
File Format PDF
Copyright Year ©2006
Language English
Subject Domain (in DDC) Technology ♦ Medicine & health
Subject Keyword Neurosciences ♦ Computer Application in Life Sciences ♦ Neurobiology ♦ Bioinformatics ♦ Statistical Physics, Dynamical Systems and Complexity
Abstract We show that an ongoing locomotor pattern can be dynamically controlled by applying discrete pulses of electrical stimulation to the central pattern generator (CPG) for locomotion. Data are presented from a pair of experiments on biological (wetware) and electrical (hardware) models of the CPG demonstrating that stimulation causes brief deviations from the CPG’s limit cycle activity. The exact characteristics of the deviation depend strongly on the phase of stimulation. Applications of this work are illustrated by examples showing how locomotion can be controlled by using a feedback loop to monitor CPG activity and applying stimuli at the appropriate times to modulate motor output. Eventually, this approach could lead to development of a neuroprosthetic device for restoring locomotion after paralysis.
ISSN 03401200
Age Range 18 to 22 years ♦ above 22 year
Educational Use Research
Education Level UG and PG
Learning Resource Type Article
Publisher Date 2006-11-18
Publisher Place Berlin/Heidelberg
e-ISSN 14320770
Journal Biological Cybernetics
Volume Number 95
Issue Number 6
Page Count 12
Starting Page 555
Ending Page 566


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Source: SpringerLink