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Author Loenneke, Jeremy P. ♦ Fahs, Christopher A. ♦ Heffernan, Kevin S. ♦ Rossow, Lindy M. ♦ Thiebaud, Robert S. ♦ Bemben, Michael G.
Source SpringerLink
Content type Text
Publisher Springer-Verlag
File Format PDF
Copyright Year ©2012
Language English
Subject Domain (in DDC) Technology ♦ Medicine & health
Subject Keyword Resistance training ♦ Cardiovascular ♦ Blood pressure ♦ Muscle cross-sectional area ♦ Fat mass ♦ Strength ♦ Human Physiology ♦ Occupational Medicine/Industrial Medicine ♦ Sports Medicine
Abstract Skeletal muscle may be viewed as an endocrine organ that releases numerous factors with the potential to influence vascular tone. Previous cross-sectional studies have shown an inverse relationship between muscle mass and arterial stiffness. We examined the relationship between muscle mass, arterial pressure in the aorta and brachial artery, and pressure from wave reflections [characterized as heart rate corrected augmentation pressure (AP)] and augmentation index (AIx). Twenty-seven (13 male, 14 female) subjects who were non-smokers and had no known cardiovascular or metabolic diseases visited the laboratory for two sessions of testing. Upon arriving for the first session, mid-thigh muscle (mCSA) and fat (fCSA) cross-sectional area were assessed using peripheral Quantitative Computed Tomography. Following this, concentric one-repetition maximum (1-RM) testing was completed to assess knee extensor strength. The second visit consisted of taking brachial and aortic blood pressure measurements. A significant positive relationship was found between mCSA and brachial systolic blood pressure (r = 0.47, p = 0.02), but not between mCSA and aortic systolic blood pressure (r = 0.35, p = 0.09). There was an inverse association between mCSA and AP75 (−0.49, p = 0.01) and AIx75 (−0.49, p = 0.01). In conclusion, muscle mass is associated with brachial systolic blood pressure and inversely associated with pressure from wave reflections. Our findings suggest a link between global musculo-skeletal integrity and cardiovascular hemodynamics in young healthy adults.
ISSN 14396319
Age Range 18 to 22 years ♦ above 22 year
Educational Use Research
Education Level UG and PG
Learning Resource Type Article
Publisher Date 2012-07-06
Publisher Place Berlin/Heidelberg
e-ISSN 14396327
Journal European Journal of Applied Physiology
Volume Number 113
Issue Number 2
Page Count 7
Starting Page 395
Ending Page 401

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Source: SpringerLink