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Author Castro, K. N. C. ♦ Lima, D. F. ♦ Vasconcelos, L. C. ♦ Leite, J. R. S. A. ♦ Santos, R. C. ♦ Paz Neto, A. A. ♦ Costa Júnior, L. M.
Source SpringerLink
Content type Text
Publisher Springer Berlin Heidelberg
File Format PDF
Copyright Year ©2014
Language English
Subject Domain (in DDC) Technology ♦ Medicine & health
Subject Keyword Cattle ♦ Control ♦ Extract ♦ Tick ♦ Medical Microbiology ♦ Microbiology ♦ Immunology
Abstract Cattle tick control has been limited by the resistance of these parasites to synthetic acaricides. Natural products are a possible alternative as they have different mechanisms of action. Acmella oleracea is a native plant with a large cultivated area in the Amazon region and could be easily used for large-scale preparation of a commercial product. This study evaluated the in vitro action of the hexane extract of the aerial parts of A. oleracea on larvae and engorged females of the cattle tick Rhipicephalus microplus. Spilanthol was the major constituent with a content of 14.8 % in the extract. The hexane extract of A. oleracea was highly effective against larvae of R. microplus with an LC50 of 0.8 mg mL−1. Against engorged females, hexane extract of A. oleracea reduced oviposition and hatchability of eggs with an LC50 of 79.7 mg mL−1. Larvae and engorged females were killed by the hexane extract with high efficiency (>95 %) at concentrations of 3.1 and 150.0 mg mL−1, respectively. These results demonstrate that the hexane extract of A. oleracea has significant activity against R. microplus and has potential to be developed into formulations for tick control.
ISSN 09320113
Age Range 18 to 22 years ♦ above 22 year
Educational Use Research
Education Level UG and PG
Learning Resource Type Article
Publisher Date 2014-07-18
Publisher Place Berlin/Heidelberg
e-ISSN 14321955
Journal Parasitology Research
Volume Number 113
Issue Number 10
Page Count 5
Starting Page 3697
Ending Page 3701


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Source: SpringerLink