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Author Stefaniuk, Monika ♦ Ropka Molik, Katarzyna
Source SpringerLink
Content type Text
Publisher Springer Berlin Heidelberg
File Format PDF
Copyright Year ©2015
Language English
Subject Domain (in DDC) Natural sciences & mathematics ♦ Life sciences; biology
Subject Keyword Equus caballus ♦ Horse ♦ miRNA ♦ RNA-seq ♦ Transcriptome ♦ Plant Genetics & Genomics ♦ Human Genetics ♦ Animal Genetics and Genomics ♦ Microbial Genetics and Genomics
Abstract RNA sequencing (RNA-seq) by next-generation technology is a powerful tool which creates new possibilities in whole-transcriptome analysis. In recent years, with the use of the RNA-seq method, several studies expanded transcriptional gene profiles to understand interactions between genotype and phenotype, supremely contributing to the field of equine biology. To date, in horses, massive parallel sequencing of cDNA has been successfully used to identify and quantify mRNA levels in several normal tissues, as well as to annotate genes. Moreover, the RNA-seq method has been applied to identify the genetic basis of several diseases or to investigate organism adaptation processes to the training conditions. The use of the RNA-seq approach has also confirmed that horses can be useful as a large animal model for human disease, especially in the field of immune response. The presented review summarizes the achievements of profiling gene expression in horses (Equus caballus).
ISSN 12341983
Age Range 18 to 22 years ♦ above 22 year
Educational Use Research
Education Level UG and PG
Learning Resource Type Article
Publisher Date 2015-10-07
Publisher Place Berlin, Heidelberg
e-ISSN 21903883
Journal Journal of Applied Genetics
Volume Number 57
Issue Number 2
Page Count 8
Starting Page 199
Ending Page 206


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Source: SpringerLink