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Author Cohrs, Randall J. ♦ Badani, Hussain ♦ Bos, Nathan ♦ Scianna, Charles ♦ Hoskins, Ian ♦ Baird, Nicholas L. ♦ Gilden, Don
Source SpringerLink
Content type Text
Publisher Springer International Publishing
File Format PDF
Copyright Year ©2016
Language English
Subject Domain (in DDC) Technology ♦ Medicine & health
Subject Keyword HSV-1 ♦ VZV ♦ DNA ♦ Human trigeminal ganglia ♦ Reactivation ♦ Neurosciences ♦ Virology ♦ Infectious Diseases ♦ Immunology ♦ Neurology
Abstract Analysis of the frequency and PCR-quantifiable abundance of herpes simplex virus type 1 (HSV-1) and varicella zoster virus (VZV) DNA in multiple biological replicates of cells from dissociated randomly distributed human trigeminal ganglia (TG) of four subjects revealed an increase in both parameters and in both viruses during 5 days of culture, with no further change by 10 days. Dissociated TG provides a platform to analyze initiation of latent virus DNA replication within 5 days of culture.
ISSN 13550284
Age Range 18 to 22 years ♦ above 22 year
Educational Use Research
Education Level UG and PG
Learning Resource Type Article
Publisher Date 2016-05-12
Publisher Place Cham, Switzerland
e-ISSN 15382443
Journal Journal of NeuroVirology
Volume Number 22
Issue Number 5
Page Count 7
Starting Page 688
Ending Page 694


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Source: SpringerLink