|Author||Cohrs, Randall J. ♦ Badani, Hussain ♦ Bos, Nathan ♦ Scianna, Charles ♦ Hoskins, Ian ♦ Baird, Nicholas L. ♦ Gilden, Don|
|Publisher||Springer International Publishing|
|Subject Domain (in DDC)||Technology ♦ Medicine & health|
|Subject Keyword||HSV-1 ♦ VZV ♦ DNA ♦ Human trigeminal ganglia ♦ Reactivation ♦ Neurosciences ♦ Virology ♦ Infectious Diseases ♦ Immunology ♦ Neurology|
|Abstract||Analysis of the frequency and PCR-quantifiable abundance of herpes simplex virus type 1 (HSV-1) and varicella zoster virus (VZV) DNA in multiple biological replicates of cells from dissociated randomly distributed human trigeminal ganglia (TG) of four subjects revealed an increase in both parameters and in both viruses during 5 days of culture, with no further change by 10 days. Dissociated TG provides a platform to analyze initiation of latent virus DNA replication within 5 days of culture.|
|Age Range||18 to 22 years ♦ above 22 year|
|Education Level||UG and PG|
|Learning Resource Type||Article|
|Publisher Place||Cham, Switzerland|
|Journal||Journal of NeuroVirology|
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