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Author Kotzerke, J. ♦ Stibane, C. ♦ Dralle, H. ♦ Wiese, H. ♦ Burchert, W.
Source United States Department of Energy Office of Scientific and Technical Information
Content type Text
Language English
Subject Keyword RADIOLOGY AND NUCLEAR MEDICINE ♦ ADRENAL GLANDS ♦ NEOPLASMS ♦ DIAGNOSIS ♦ EMISSION COMPUTED TOMOGRAPHY ♦ ENDOCRINE DISEASES ♦ IODINE ISOTOPES ♦ MAN ♦ NMR IMAGING ♦ PATIENTS ♦ SCINTISCANNING ♦ SENSITIVITY ANALYSIS ♦ ULTRASONOGRAPHY ♦ ANIMALS ♦ BODY ♦ COMPUTERIZED TOMOGRAPHY ♦ COUNTING TECHNIQUES ♦ DIAGNOSTIC TECHNIQUES ♦ DISEASES ♦ ENDOCRINE GLANDS ♦ GLANDS ♦ ISOTOPES ♦ MAMMALS ♦ ORGANS ♦ PRIMATES ♦ RADIOISOTOPE SCANNING ♦ TOMOGRAPHY ♦ VERTEBRATES 550601* -- Medicine-- Unsealed Radionuclides in Diagnostics ♦ Medicine
Abstract Twenty-two patients with the multiple endocrine neoplasia type 2 (MEN 2) syndrome were screened for pheochromocytoma since it is a major cause of morbidity in MEN 2 families. Clinical symptoms, biochemical parameters, ultrasound, computed tomography or magnetic resonance imaging, and meta-iodo-benzylguanidine (MIBG) scintigraphy were evaluated for detection of adrenal tumors. Clinical symptoms and plasma or urine catecholamines appeared to be nonspecific, whereas MIBG scintigraphy was highly specific and the most sensitive parameter. Patients older than age 30 should be scintigraphically screened at least once despite the radiation exposure. Demonstration of only slight uptake is not an indication for surgery but rather for careful follow-up.
ISSN 00180416
Educational Use Research
Learning Resource Type Article
Publisher Date 1989-01-01
Publisher Place United States
Journal Henry Ford Hospital Medical Journal
Volume Number 37
Issue Number 3-4


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