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Author Rowe, L. D. ♦ Lane, R. ♦ Snow, J. B. (Jr.)
Source United States Department of Energy Office of Scientific and Technical Information
Content type Text
Language English
Subject Keyword RADIATION, THERMAL, AND OTHER ENVIRON. POLLUTANT EFFECTS ON LIVING ORGS. AND BIOL. MAT. ♦ RADIOLOGY AND NUCLEAR MEDICINE ♦ CARCINOMAS ♦ RADIOINDUCTION ♦ PHARYNX ♦ DELAYED RADIATION EFFECTS ♦ RADIOTHERAPY ♦ SIDE EFFECTS ♦ HISTOLOGY ♦ BIOLOGICAL EFFECTS ♦ BIOLOGICAL RADIATION EFFECTS ♦ BODY ♦ DIGESTIVE SYSTEM ♦ DISEASES ♦ MEDICINE ♦ NEOPLASMS ♦ NUCLEAR MEDICINE ♦ ORGANS ♦ RADIATION EFFECTS ♦ RADIOLOGY ♦ RESPIRATORY SYSTEM ♦ THERAPY ♦ Radiation Effects on Animals- Man ♦ Medicine- External Radiation in Therapy- (1980-)
Abstract Adenocarcinoma of the ethmoid sinus is rare, representing only 4 to 8% of malignancies of the paranasal sinuses. An extraordinary case of papillary adenocarcinoma of the ethmoid sinus arising 30 years following high-dose radiotherapy for bilateral retinoblastoma is presented. Histologically, the findings of a papillary pattern of poorly differentiated, mucicarmine-staining cells enclosing gland-like spaces, and the absence of pseudorosettes, melanin, mesenchymal and peripheral neural elements supports an epithelial origin of this tumor. The high incidence of second fatal primary neoplasms in patients with bilateral retinoblastomas receiving radiation suggests an innate susceptibility that may add to the risk of radiotherapy. Careful long-term head and neck surveillance is mandatory if early aggressive management of these extremely lethal tumors is to be successful.
Educational Use Research
Learning Resource Type Article
Publisher Date 1980-01-01
Publisher Place United States
Journal Laryngoscope
Volume Number 80
Issue Number 1
Organization Univ. of California, San Francisco


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