Thumbnail
Access Restriction
Open

Author Von Schalburg, Kristian R. ♦ Sherwood, Nancy M.
Source Paperity
Content type Text
Publisher Oxford University Press
File Format PDF ♦ HTM / HTML
Copyright Year ©1999
Abstract The GnRH gene is transcribed in both the brain and gonads. GnRH in the brain is critical for reproduction, but the function and importance of GnRH in the ovary and testis is not clear. In this study we examine whether regulation of the GnRH gene is distinct in the brain and gonads, whether the regulation of the GnRH gene in the gonads is altered after genome duplication, and whether the regulatory region of the GnRH gene is tightly conserved in vertebrates. From ovary and testis, we isolated and sequenced for the first time two different genes and their complementary DNAs that encode the identical peptide known as salmon GnRH. Rainbow trout were selected because they are tetraploid due to genome duplication.
Learning Resource Type Article
Publisher Date 1999-07-01
Journal Endocrinology
Volume Number 140
Issue Number 7