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Author Moroff, S. V.
Source United States Department of Energy Office of Scientific and Technical Information
Content type Text
Language English
Subject Keyword RADIATION, THERMAL, AND OTHER ENVIRON. POLLUTANT EFFECTS ON LIVING ORGS. AND BIOL. MAT. ♦ HODGKINS DISEASE ♦ RADIOTHERAPY ♦ SIDE EFFECTS ♦ THYROID ♦ CARCINOMAS ♦ DELAYED RADIATION EFFECTS ♦ HYPOTHYROIDISM ♦ RADIOINDUCTION ♦ BIOLOGICAL EFFECTS ♦ BIOLOGICAL RADIATION EFFECTS ♦ BODY ♦ DISEASES ♦ ENDOCRINE DISEASES ♦ ENDOCRINE GLANDS ♦ GLANDS ♦ LYMPHOMAS ♦ MEDICINE ♦ NEOPLASMS ♦ NUCLEAR MEDICINE ♦ ORGANS ♦ RADIATION EFFECTS ♦ RADIOLOGY ♦ THERAPY ♦ Radiation Effects on Animals- Man
Abstract Improved survival resulting from advances in therapy in patients with Hodgkin's disease is associated with long-term morbidity, including the potential for the development of a second solid malignancy. We report a 44-year-old man with an unusually aggressive course of thyroid carcinoma 15 years after treatment for Hodgkin's disease. In a review of the English-language literature, we found 21 cases of thyroid cancer following radiotherapy for Hodgkin's disease, with latency periods ranging from 6 to 48 years. The development of secondary thyroid cancer after high-dose neck irradiation may be related to hypothyroidism, itself a complication of radiotherapy. Thyroid function should be measured at least once a year in all patients given neck irradiation, with initiation of thyroid hormone replacement if there is evidence of sustained hypothyroidism.
Educational Use Research
Learning Resource Type Report
Publisher Date 1986-01-01
Publisher Place United States
Journal Med. Pediatr. Oncol.
Volume Number 4
Organization Albert Einstein College of Medicine, Bronx, NY


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