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Author Minton, J. P. ♦ Mojzisik, C. ♦ Ferrara, P. J. ♦ Hinkle, G. H. ♦ Thurston, M. O. ♦ Martin, E. W. (Jr.)
Source United States Department of Energy Office of Scientific and Technical Information
Content type Text
Language English
Subject Keyword RADIOLOGY AND NUCLEAR MEDICINE ♦ LIMBS ♦ RADIATION MONITORING ♦ SELF-POWERED GAMMA DETECTORS ♦ ACCURACY ♦ ANTINEOPLASTIC DRUGS ♦ DTPA ♦ GAMMA RADIATION ♦ HYPERTHERMIA ♦ ISOMERIC NUCLEI ♦ LEAK DETECTORS ♦ MELANOMAS ♦ PATIENTS ♦ PERFUSED TISSUES ♦ RADIATION PROTECTION ♦ SKIN ♦ TECHNETIUM 99 ♦ AMINO ACIDS ♦ ANIMAL TISSUES ♦ BETA DECAY RADIOISOTOPES ♦ BETA-MINUS DECAY RADIOISOTOPES ♦ BODY ♦ BODY AREAS ♦ BODY TEMPERATURE ♦ CARBOXYLIC ACIDS ♦ CHELATING AGENTS ♦ DISEASES ♦ DRUGS ♦ ELECTROMAGNETIC RADIATION ♦ HOURS LIVING RADIOISOTOPES ♦ INTERMEDIATE MASS NUCLEI ♦ IONIZING RADIATIONS ♦ ISOMERIC TRANSITION ISOTOPES ♦ ISOTOPES ♦ MEASURING INSTRUMENTS ♦ MONITORING ♦ NEOPLASMS ♦ NUCLEI ♦ ODD-EVEN NUCLEI ♦ ORGANIC ACIDS ♦ ORGANIC COMPOUNDS ♦ ORGANS ♦ RADIATION DETECTORS ♦ RADIATIONS ♦ RADIOISOTOPES ♦ RADIOPROTECTIVE SUBSTANCES ♦ SELF-POWERED DETECTORS ♦ TECHNETIUM ISOTOPES ♦ TISSUES ♦ YEARS LIVING RADIOISOTOPES ♦ Medicine- Unsealed Radionuclides in Diagnostics
Abstract We used two hand-held gamma-detecting probes (GDP) (Neoprobe 1000 system) capable of detecting small gamma emissions to monitor leakage in patients undergoing hyperthermic isolated limb perfusion (HILP) who received 800 microCi Technetium 99m pentetate through the perfusate. The percentage of gamma-ray leakage was calculated by a simultaneous reading of two probes at 1-minute intervals (one over the precordial area and one over the thigh) and this was compared to results of simultaneous blood sampling from the perfusate and systemic circulation at 15-minute intervals for gamma well counting (GWC). The percentage of leakage recorded by the GDPs was essentially identical to that detected by the GWC (7.3% and 8.2%, respectively at the conclusion of the perfusion). The GDP gives an immediate and accurate indication of the percentage of leakage during HILP, making it a safer procedure.
Educational Use Research
Learning Resource Type Article
Publisher Date 1989-07-01
Publisher Place United States
Journal J. Surg. Oncol.
Volume Number 41
Issue Number 3
Organization Ohio State Univ. College of Medicine, Columbus (USA)


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