|Author||Wang, Stanley C. ♦ Kuskin, Jeffrey S. ♦ Shan, Yibing ♦ Towles, Brian ♦ Shaw, David E. ♦ Mueller, Rolf ♦ Dror, Ron O. ♦ Larson, Richard H. ♦ Salmon, John K. ♦ Eastwood, Michael P. ♦ Grossman, J. P. ♦ Layman, Timothy ♦ Ho, C. Richard ♦ Deneroff, Martin M. ♦ Gagliardo, Joseph ♦ Spengler, Jochen ♦ Ierardi, Douglas J. ♦ Moraes, Mark A. ♦ Young, Cliff ♦ Chao, Jack C. ♦ Kolossváry, István ♦ Batson, Brannon ♦ Bowers, Kevin J. ♦ McLeavey, Christine ♦ Theobald, Michael ♦ Klepeis, John L. ♦ Priest, Edward C.|
|Source||ACM Digital Library|
|Publisher||Association for Computing Machinery (ACM)|
|Abstract||The ability to perform long, accurate molecular dynamics (MD) simulations involving proteins and other biological macro-molecules could in principle provide answers to some of the most important currently outstanding questions in the fields of biology, chemistry, and medicine. A wide range of biologically interesting phenomena, however, occur over timescales on the order of a millisecond---several orders of magnitude beyond the duration of the longest current MD simulations. We describe a massively parallel machine called Anton, which should be capable of executing millisecond-scale classical MD simulations of such biomolecular systems. The machine, which is scheduled for completion by the end of 2008, is based on 512 identical MD-specific ASICs that interact in a tightly coupled manner using a specialized highspeed communication network. Anton has been designed to use both novel parallel algorithms and special-purpose logic to dramatically accelerate those calculations that dominate the time required for a typical MD simulation. The remainder of the simulation algorithm is executed by a programmable portion of each chip that achieves a substantial degree of parallelism while preserving the flexibility necessary to accommodate anticipated advances in physical models and simulation methods.|
|Description||Affiliation: D.E. Shaw Research, New York, NY (Deneroff, Martin M.; Dror, Ron O.; Kuskin, Jeffrey S.; Larson, Richard H.; Salmon, John K.; Young, Cliff; Batson, Brannon; Bowers, Kevin J.; Chao, Jack C.; Eastwood, Michael P.; Gagliardo, Joseph; Grossman, J. P.; Ho, C. Richard; Ierardi, Douglas J.; Kolossváry, István; Klepeis, John L.; Layman, Timothy; McLeavey, Christine; Moraes, Mark A.; Mueller, Rolf; Priest, Edward C.; Shan, Yibing; Spengler, Jochen; Theobald, Michael; Towles, Brian; Wang, Stanley C.) || D.E. Shaw Research, New York, NY and Columbia University, New York, NY (Shaw, David E.)|
|Age Range||18 to 22 years ♦ above 22 year|
|Education Level||UG and PG|
|Learning Resource Type||Article|
|Publisher Place||New York|
|Journal||Communications of the ACM (CACM)|
Ministry of Human Resource Development (MHRD) under its National Mission on Education through Information and Communication Technology (NMEICT) has initiated the National Digital Library of India (NDLI) project to develop a framework of virtual repository of learning resources with a single-window search facility. Filtered and federated searching is employed to facilitate focused searching so that learners can find out the right resource with least effort and in minimum time. NDLI is designed to hold content of any language and provides interface support for leading vernacular languages, (currently Hindi, Bengali and several other languages are available). It is designed to provide support for all academic levels including researchers and life-long learners, all disciplines, all popular forms of access devices and differently-abled learners. It is being developed to help students to prepare for entrance and competitive examinations, to enable people to learn and prepare from best practices from all over the world and to facilitate researchers to perform inter-linked exploration from multiple sources. It is being developed at Indian Institute of Technology Kharagpur.
NDLI is a conglomeration of freely available or institutionally contributed or donated or publisher managed contents. Almost all these contents are hosted and accessed from respective sources. The responsibility for authenticity, relevance, completeness, accuracy, reliability and suitability of these contents rests with the respective organization and NDLI has no responsibility or liability for these. Every effort is made to keep the NDLI portal up and running smoothly unless there are some unavoidable technical issues.
Ministry of Human Resource Development (MHRD), through its National Mission on Education through Information and Communication Technology (NMEICT), has sponsored and funded the National Digital Library of India (NDLI) project.
For any issue or feedback, please write to firstname.lastname@example.org