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Author Juffrie, Mohammad ♦ Utama, Made Gde Dwi Lingga ♦ Purnami, Ni Made Adi
Source Directory of Open Access Journals (DOAJ)
Content type Text
Publisher Indonesian Pediatric Society Publishing House
File Format HTM / HTML
Date Created 2016-07-25
Copyright Year ©2015
Language English
Subject Domain (in LCC) R ♦ RJ1-570
Subject Keyword Severity ♦ Pediatrics ♦ Dengue infection ♦ Medicine ♦ SNS1
Abstract Background Dengue infection is one of the main cause of morbidity and mortality in children in Indonesia. Since it is known that earlier treatment and supportive therapies can decreased case fatality rate from dengue hemorrhagic fever (DHF), identification of children who have risks to develop to DHF must be quickly identified, mainly in areas of endemic. Objective To find a correlation between increased quantitative secreted nonstructural protein-1 (sNS1) with clinical course of severe dengue infections. Methods This was a cross-sectional study conducted on children with dengue infections in Tropical Infections Division of Child Health Department, Sanglah Hospital, Denpasar. Detection of the dengue antigen was made by examining sNS1 quantitative immuno-assay. Analysis correlation of Spearman test was used to look the relationship between increased quantitative sNS1 with clinical course of severe dengue infections. Results There was a positive relationship between quantitative sNS1 and clinical course of severe dengue infections with a value of r = 0.903, P=0.001. Increased sNS1 level had a positive correlation with more severe dengue infections. Conclusions Quantitative sNS1 titer has a strong positive correlation with clinical course of severe dengue infections.
ISSN 00309311
Age Range 18 to 22 years ♦ above 22 year
Educational Use Research
Education Level UG and PG ♦ Career/Technical Study
Learning Resource Type Article
Publisher Date 2015-04-01
e-ISSN 00309311
Journal Paediatrica Indonesiana
Volume Number 55
Issue Number 2
Page Count 4
Starting Page 87
Ending Page 90

Source: Directory of Open Access Journals (DOAJ)