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Author Soares, Marcos Eugenio ♦ Mollerke, Roseli De Oliveira ♦ França, Luís Henrique Gil ♦ Nóbrega, Fernanda ♦ Argenta, Rodrigo ♦ Aveline, Celso Curcio ♦ Pereira, Adamastor Humberto ♦ Ferreira, Márcio Poletto ♦ Perini, Sílvio César
Source Directory of Open Access Journals (DOAJ)
Content type Text
Publisher Sociedade Brasileira de Angiologia e de Cirurgia Vascular (SBACV)
File Format HTM / HTML
Date Created 2013-09-04
Copyright Year ©2005
Language English ♦ Portuguese
Subject Domain (in LCC) RD1-811 ♦ RC666-701
Subject Keyword Animal models ♦ Aortic aneurysm ♦ Aneurisma aórtico ♦ Internal medicine ♦ Arteries ♦ Modelos animais ♦ Medicine ♦ Artérias ♦ Specialties of internal medicine ♦ Surgery
Abstract OBJETIVO: Desenvolver um novo modelo experimental de pseudoaneurisma sacular de artéria ilíaca comum com o uso de remendo de pericárdio bovino em suínos. MÉTODO: Foram utilizados dois suínos da raça Landrace, com peso de 30 kg e do sexo feminino. Os animais foram submetidos a anestesia geral e a laparotomia com acesso extraperitoneal da aorta infra-renal e artérias ilíacas. Após heparinização sistêmica e pinçamento, foram efetuadas arteriotomia longitudinal e sutura do pericárdio bovino em formato de bolsa previamente confeccionada. Os animais permaneceram confinados por 3 semanas e então foram submetidos a arteriografia para avaliação da perviedade do aneurisma e, posteriormente, sacrificados. RESULTADO: Os animais sobreviveram ao experimento e apresentaram aneurismas pérvios no momento do sacrifício. Não houve ocorrência de ruptura de aneurismas. CONCLUSÃO: O modelo proposto é viável e tem potencial para ser utilizado no estudo e desenvolvimento de novas próteses endovasculares.OBJECTIVE: To develop an experimental model of saccular pseudoaneurysm of the common iliac artery with bovine pericardium in pigs. METHOD: The animals used were two 30-kg female pigs from the Landrace specimen. The animals were submitted to general anesthesia and laparotomy with extraperitoneal access to infrarenal aorta and the iliac arteries. After systemic heparin and clamping, the iliac artery was opened and the pericardium sutured to the vessel wall. All animals were confined for 3 weeks and were sacrificed after performing an arteriography to verify the patency of the aneurysm. RESULT: All animals survived the procedure and the aneurysms were patent. No rupture was detected. CONCLUSION: This is a feasible pig model of iliac artery aneurysm with potential for further studies to develop new endovascular prostheses.
ISSN 16777301
Age Range 18 to 22 years ♦ above 22 year
Educational Use Research
Education Level UG and PG ♦ Career/Technical Study
Learning Resource Type Article
Publisher Date 2005-01-01
e-ISSN 16775449
Journal Jornal Vascular Brasileiro
Volume Number 4
Issue Number 4
Page Count 4
Starting Page 353
Ending Page 356


Source: Directory of Open Access Journals (DOAJ)