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Author Tomazinisantos, Izolete Aparecida ♦ Gianini, Mariangela ♦ Mórbio, Ana Paula ♦ Sobreira, Marcone Lima ♦ Carvalho, Lidia Raquel De ♦ Maffei, Francisco Humberto De Abreu ♦ Arbex, Paulo Eduardo ♦ Santos, Fernada Cardoso
Source Directory of Open Access Journals (DOAJ)
Content type Text
Publisher Sociedade Brasileira de Angiologia e de Cirurgia Vascular (SBACV)
File Format HTM / HTML
Date Created 2013-09-04
Copyright Year ©2006
Language English ♦ Portuguese
Subject Domain (in LCC) RD1-811 ♦ RC666-701
Subject Keyword Trombose venosa ♦ Anticoagulantes ♦ Internal medicine ♦ Efeitos adversos ♦ Medicine ♦ Embolia pulmonar ♦ Doenças vasculares ♦ Specialties of internal medicine ♦ Warfarin ♦ Warfarina ♦ Vascular diseases ♦ Anticoagulants ♦ Adverse effects ♦ Pulmonary embolism ♦ Venous thrombosis ♦ Surgery
Abstract OBJETIVO: Estudar prospectivamente a freqüência de complicações em pacientes tratados com warfarina e acompanhados no Ambulatório de Anticoagulação da Faculdade de Medicina de Botucatu da Universidade Estadual Paulista. MÉTODOS: Pacientes sorteados entre os agendados para consulta de junho de 2002 a fevereiro de 2004. Na primeira consulta, foi preenchida ficha com dados de identificação e clínicos. A cada retorno, ou quando o paciente procurou o hospital por intercorrência, foi preenchida ficha com a razão normatizada internacional, existência e tipo de intercorrência e condições de uso dos antagonistas da vitamina K. RESULTADOS: Foram acompanhados 136 pacientes (61 homens e 75 mulheres), 99 com tromboembolismo venoso e 37 com doença arterial; 59 pacientes eram de Botucatu, e 77, de outros municípios. Foram registradas 30 intercorrências: nove não relacionadas ao uso da warfarina e 21 complicações hemorrágicas (38,8 por 100 pacientes/ano). Uma hematêmese foi considerada grave (1,9 por 100 pacientes/ano). As demais foram consideradas moderadas ou leves. Não houve óbitos, hemorragia intracraniana ou necrose cutânea. A única associação significante foi da freqüência de hemorragia com nível médio de razão normatizada internacional. CONCLUSÃO: Nossos resultados mostram a viabilidade desse tratamento em pacientes vasculares em nosso meio, mesmo em população de baixo nível socioeconômico, quando tratados em ambulatório especializado.OBJECTIVE: To prospectively study the frequency of complications in patients treated with warfarin followed at Botucatu Medical School. METHODS: Patients randomly selected among those with appointments scheduled from June 2002 to February 2004. At the first appointment, a protocol was filled with identification and clinical data. At every return or when the patient went to the hospital due to clinical events, another form was filled with the international normalized ratio, existence and type of clinical event and the conditions of use of vitamin K antagonists. RESULTS: A total of 136 patients (61 men and 75 women), were followed; 99 patients with venous thromboembolism and 37 with arterial disease; 59 were from Botucatu and 77 were from other municipalities. Thirty clinical events were registered: nine of them were not related to the use of warfarin and 21 were hemorrhagic complications (38.8 per 100 patients-year). One hematemesis was considered severe (1.9 per 100 patients-year). The others were considered moderate or mild. There were no deaths, intracranial hemorrhage or cutaneous necrosis. The only significant association was frequency of hemorrhage and average international normalized ratio level. CONCLUSION: Our results demonstrate the feasibility of this treatment in vascular patients in our country, even in socially and economically poor populations, when treated in specialized clinics.
ISSN 16777301
Age Range 18 to 22 years ♦ above 22 year
Educational Use Research
Education Level UG and PG ♦ Career/Technical Study
Learning Resource Type Article
Publisher Date 2006-09-01
e-ISSN 16775449
Journal Jornal Vascular Brasileiro
Volume Number 5
Issue Number 3
Page Count 9
Starting Page 194
Ending Page 202


Source: Directory of Open Access Journals (DOAJ)