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Author Cohen, Jacques
Source ACM Digital Library
Content type Text
Publisher Association for Computing Machinery (ACM)
File Format PDF
Copyright Year ©2004
Language English
Subject Domain (in DDC) Computer science, information & general works ♦ Data processing & computer science
Subject Keyword DNA ♦ Molecular cell biology ♦ RNA and protein structure ♦ Alignments ♦ Cell simulation and modeling ♦ Computer ♦ Dynamic programming ♦ Hidden-Markov-models ♦ Microarray ♦ Parsing biological sequences ♦ Phylogenetic trees
Abstract The article aims to introduce computer scientists to the new field of bioinformatics. This area has arisen from the needs of biologists to utilize and help interpret the vast amounts of data that are constantly being gathered in genomic research---and its more recent counterparts, proteomics and functional genomics. The ultimate goal of bioinformatics is to develop in silico models that will complement in vitro and in vivo biological experiments. The article provides a bird's eye view of the basic concepts in molecular cell biology, outlines the nature of the existing data, and describes the kind of computer algorithms and techniques that are necessary to understand cell behavior. The underlying motivation for many of the bioinformatics approaches is the evolution of organisms and the complexity of working with incomplete and noisy data. The topics covered include: descriptions of the current software especially developed for biologists, computer and mathematical cell models, and areas of computer science that play an important role in bioinformatics.
ISSN 03600300
Age Range 18 to 22 years ♦ above 22 year
Educational Use Research
Education Level UG and PG
Learning Resource Type Article
Publisher Date 2004-06-01
Publisher Place New York
e-ISSN 15577341
Journal ACM Computing Surveys (CSUR)
Volume Number 36
Issue Number 2
Page Count 37
Starting Page 122
Ending Page 158


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Source: ACM Digital Library