|Author||Ogata-Suetsugu, Saiko ♦ Maeyama, Takashige ♦ Takeshita, Masafumi ♦ Hamada, Naoki ♦ Takayama, Koichi ♦ Inoue, Hiromasa ♦ Nakanishi, Yoichi|
|Publisher||The Editorial Committee of Annals of Thoracic and Cardiovascular Surgery|
|Subject Keyword||primary pulmonary lymphoma (PPL) ♦ diffuse ground-glass shadows ♦ immunoglobulin heavy chain gene rearrangement|
|Abstract||We report a case of 77-year-old woman suffering from breathlessness on exertion and dry cough. Chest computed tomography (CT) showed diffuse ground-glass shadows. A video-assisted thoracoscopic lung biopsy resulted in the diagnosis of diffuse large B-cell lymphoma (DLBCL). Gene rearrangement analysis using polymerase chain reaction (PCR) technique was performed on the cells in bronchoalveolar lavage (BAL) fluid, and showed the clonality of the immunoglobulin heavy chain (IgH) gene, supporting the diagnosis. DLBCL should be considered in the differential diagnosis of diffuse ground-glass shadows in the chest CT, and gene rearrangement analysis may have an impact on the diagnosis of pulmonary DLBCL.|
|Learning Resource Type||Report|
|Journal||Annals of Thoracic and Cardiovascular Surgery(atcs)|
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