|Author||Schulze-Hagen, Maximilian Franz ♦ Pfeffer, Jochen ♦ Zimmermann, Markus ♦ Liebl, Martin ♦ Stillfried, Saskia Freifrau von ♦ Kuhl, Christiane ♦ Bruners, Philipp ♦ Isfort, Peter|
|Source||United States Department of Energy Office of Scientific and Technical Information|
|Subject Keyword||RADIOLOGY AND NUCLEAR MEDICINE ♦ ANIMAL TISSUES ♦ BIOPSY ♦ COMPUTERIZED TOMOGRAPHY ♦ HAZARDS ♦ HISTOLOGY ♦ LIVER ♦ MUSCLES ♦ NICKEL ALLOYS ♦ PHANTOMS ♦ SHAPE MEMORY EFFECT ♦ SWINE ♦ TITANIUM ALLOYS|
|Abstract||PurposeTo evaluate the feasibility of a novel curved CT-guided biopsy needle prototype with shape memory to access otherwise not accessible biopsy targets.Methods and MaterialsA biopsy needle curved by 90° with specific radius was designed. It was manufactured using nitinol to acquire shape memory, encased in a straight guiding trocar to be driven out for access of otherwise inaccessible targets. Fifty CT-guided punctures were conducted in a biopsy phantom and 10 CT-guided punctures in a swine corpse. Biposies from porcine liver and muscle tissue were separately gained using the biopsy device, and histological examination was performed subsequently.ResultsMean time for placement of the trocar and deployment of the inner biopsy needle was ~205 ± 69 and ~93 ± 58 s, respectively, with a mean of ~4.5 ± 1.3 steps to reach adequate biopsy position. Mean distance from the tip of the needle to the target was ~0.7 ± 0.8 mm. CT-guided punctures in the swine corpse took relatively longer and required more biopsy steps (~574 ± 107 and ~380 ± 148 s, 8 ± 2.6 steps). Histology demonstrated appropriate tissue samples in nine out of ten cases (90%).ConclusionsTargets that were otherwise inaccessible via standard straight needle trajectories could be successfully reached with the curved biopsy needle prototype. Shape memory and preformed size with specific radius of the curved needle simplify the target accessibility with a low risk of injuring adjacent structures.|
|Learning Resource Type||Article|
|Publisher Place||United States|
|Journal||Cardiovascular and Interventional Radiology|
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