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Author Jevrićčaušević, Adlija
Source Directory of Open Access Journals (DOAJ)
Content type Text
Publisher Association of Basic Medical Sciences of Federation of Bosnia and Herzegovina
File Format HTM / HTML
Date Created 2018-05-29
Copyright Year ©1998
Language English
Subject Domain (in LCC) R5-920
Subject Keyword C6 glioma ♦ Antiproliferative effects ♦ Medicine ♦ Ganglioside GMI ♦ Cytotoxicity ♦ SarCNU
Abstract In vitro antiproliferative effects of SarCNU and GMI ganglioside were tested in different concentration ratios in C6 glioma cell culture. Based on MTT assay and a protein assay, cytotoxicity of each agent separately and the two agents combined was tested. When the cells were treated with different concentrations of ganglioside ranging from 10-’ to 10-2, the number of viable cells decreased highly on days two and seven, regardless of the concentration of the agent applied. SarCNU, as expected, has caused antiproliferative effects which highly correlated with the concentration of the agent tested. When the C6 glioma cell culture was treated with the two agents combined in the optimal concentration causing the above mentioned cytotoxicity, effects observed did not correlate with those observed for each agent alone, suggesting in this case the expression of highly neuroprotective effects of ganglioside GMI.
ISSN 15128601
Age Range 18 to 22 years ♦ above 22 year
Educational Use Research
Education Level UG and PG ♦ Career/Technical Study
Learning Resource Type Article
Publisher Date 1998-02-01
e-ISSN 15128601
Journal Bosnian Journal of Basic Medical Sciences
Volume Number 1
Issue Number 1
Page Count 4
Starting Page 20
Ending Page 23


Source: Directory of Open Access Journals (DOAJ)