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Author Song, J. ♦ Joshi, R. P. ♦ Schoenbach, K. H.
Source SpringerLink
Content type Text
Publisher Springer-Verlag
File Format PDF
Copyright Year ©2011
Language English
Subject Domain (in DDC) Technology ♦ Medicine & health
Subject Keyword Bioelectric ♦ Voltage pulse ♦ Nanosecond, high intensity ♦ Modeling ♦ Thermal effect ♦ Imaging ♦ Radiology ♦ Biomedical Engineering ♦ Computer Applications ♦ Human Physiology
Abstract Results of self-consistent analyses of cells show the possibility of temperature increases at membranes in response to a single nanosecond, high-voltage pulse, at least over small sections of the membrane. Molecular Dynamics simulations indicate that such a temperature increase could facilitate poration, which is one example of a bio-process at the plasma membrane. Our study thus suggests that the use of repetitive high-intensity voltage pulses could open up possibilities for a host of synergistic bio-responses involving both thermal and electrically driven phenomena.
ISSN 01400118
Age Range 18 to 22 years ♦ above 22 year
Educational Use Research
Education Level UG and PG
Learning Resource Type Article
Publisher Date 2011-02-22
Publisher Place Berlin, Heidelberg
e-ISSN 17410444
Journal Medical and Biological Engineering and Computing
Volume Number 49
Issue Number 6
Page Count 6
Starting Page 713
Ending Page 718


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Source: SpringerLink