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Author Flerov, M. A. ♦ Gerasimova, I. A.
Source SpringerLink
Content type Text
Publisher Allerton Press, Inc.
File Format PDF
Copyright Year ©2007
Language English
Subject Domain (in DDC) Technology ♦ Medicine & health
Subject Keyword lipid peroxidation ♦ brain ♦ stress ♦ individual behavioral peculiarities ♦ Neurosciences
Abstract Lipid peroxidation in the brain cortex, striatum, hippocampus, and hypothalamus of rats of the KLA and KHA lines which were distinguished by their strategies of adaptive behavior was investigated following emotional-painful stress. Significant long-term changes in lipid peroxidation were shown to occur in the brain. These had a phase character and depended on the behavioral characteristics of the animals. The investigated brain regions were characterized by different reactions of lipid peroxidation to the stress. The induced depressive-like states (on the 21st day after the stress) in rats of the KLA and KHA lines were distinguished by the largest changes in lipid peroxidation in the striatum and hypothalamus and in the striatum and hippocampus, respectively. One could conclude on the basis of these results that both identical and different mechanisms of formation and development of depression existed in the animals with different behavioral strategies.
ISSN 18197124
Age Range 18 to 22 years ♦ above 22 year
Educational Use Research
Education Level UG and PG
Learning Resource Type Article
Publisher Date 2007-01-01
Publisher Place New York
e-ISSN 18197132
Journal Neurochemical Journal
Volume Number 1
Issue Number 2
Page Count 6
Starting Page 150
Ending Page 155


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Source: SpringerLink