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Author Faria, Mário B. ♦ Kraemer, Jorge L. ♦ Lima, Leonardo C.s ♦ Pereira-Filho, Arthur A. ♦ Pereira, Adriana G.
Source Directory of Open Access Journals (DOAJ)
Content type Text
Publisher Academia Brasileira de Neurologia (ABNEURO)
File Format HTM / HTML
Date Created 2013-09-04
Copyright Year ©2010
Language English
Subject Domain (in LCC) RC321-571
Subject Keyword Aneurisma cerebral ♦ Déficit cognitivo ♦ Cerebral aneurysm ♦ Neurosciences ♦ Internal medicine ♦ Neuropsychiatry ♦ Biological psychiatry ♦ Medicine ♦ Surgical clipping ♦ Clipagem cirúrgica ♦ Mini mental state examination ♦ Mini exame do estado mental ♦ Cognitive impairment
Abstract OBJECTIVE: It is a consensus that most unruptured intracranial aneurysms (UIA) can be treated with acceptably low morbidity. However, some studies recently reported postoperative cognitive impairment, suggesting that it could be attributable to surgical damage. Our goal is to evaluate cognitive function before and after microsurgical clipping in patients with UIA. METHOD: A consecutive series of 40 patients who underwent microsurgical clipping for UIA were studied. The cognitive assessment (Mini Mental State Examination, MMSE) was performed immediately before and at least one month after surgery. Paired Student's "t" test and analysis of variance (ANOVA) were used for statistical purposes. RESULTS: The mean MMSE score in the preoperative analysis was 28.12 (SD, 1.34). In the postoperative period the mean MMSE score was 28.40 (SD, 1.46). Paired Student's "t" test was applied to the scores and no significant difference was found (p=0.315). ANOVA did not find independent associations between MMSE scores and age, hypertension, smoking, dyslipidemia, education, aneurysm location, number, laterality or size. CONCLUSION: The present study suggests that microsurgical clipping for UIA does not result in major cognitive dysfunction as determined by the MMSEOBJETIVO: É consenso que a maioria dos aneurismas intracranianos não-rotos (AINR) podem ser tratados com aceitável taxa de morbidade. Entretanto, alguns estudos reportaram déficits cognitivos no pós-operatório, sugerindo que poderiam ser atribuídos ao dano cirúrgico. O objetivo desse estudo é avaliar a função cognitiva antes e após clipagem microcirúrgica em pacientes com AINR. MÉTODO: Uma série de 40 pacientes com AINR submetidos à clipagem microcirúrgica foi estudada. A avaliação cognitiva (Mini Exame do Estado Mental, MEEM) foi realizada antes e após a intervenção cirúrgica. A análise estatística foi realizada com teste "t" de Student e análise de variância (ANOVA). RESULTADOS: A média dos escores do MEEM na análise pré-operatória foi 28,12 (DP, 1,34). No período pós-operatório, a média dos escores foi 28,40 (DP, 1,46). Não houve diferença estatística (teste "t" de Student; p=0,315). A ANOVA não encontrou associações independentes entre os escores de MEEM e idade, hipertensão, tabagismo, dislipidemia, educação e características dos aneurismas (topografia, número, lado e tamanho). CONCLUSÃO: O presente estudo sugere que a clipagem microcirúrgica não está associada a danos cognitivos maiores em pacientes com AINR
ISSN 0004282X
Age Range 18 to 22 years ♦ above 22 year
Educational Use Research
Education Level UG and PG ♦ Career/Technical Study
Learning Resource Type Article
Publisher Date 2010-10-01
e-ISSN 0004282X
Journal Arquivos de Neuro-Psiquiatria
Volume Number 68
Issue Number 5
Page Count 4
Starting Page 770
Ending Page 774


Source: Directory of Open Access Journals (DOAJ)