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Author Telford, Jennifer J. ♦ Saltzman, John R. ♦ Kuntz, Karen M. ♦ Syngal, Sapna
Source CiteSeerX
Content type Text
File Format PDF
Subject Domain (in DDC) Computer science, information & general works ♦ Data processing & computer science
Subject Keyword Preoperative Staging ♦ Decision Analysis ♦ Rectal Cancer ♦ Chemoradiation Versus Postoperative Chemoradiation ♦ Radical Resection ♦ Sur-vival Outcome ♦ Preopera-tive Staging ♦ Preoperative Chemoradiation ♦ Advanced Cancer ♦ Local Excision ♦ Rectal Cancer Management ♦ Postoperative Chemoradiation Strategy ♦ Receive Postoperative Chemoradiation ♦ Postoperative Chemoradiation ♦ Resectable Rectal Cancer ♦ Local Imaging ♦ Standard Therapy ♦ Chemoradiation Strategy ♦ Decision Model ♦ Amenable Localized Tumor ♦ Markov Model
Abstract chemoradiation have been the standard therapy for patients with rectal cancer, preoperative staging by local imaging and chemoradiation are widely used. We used a decision analysis to compare the two strategies for rectal cancer management. Methods: We developed a decision model to compare sur-vival outcomes after postoperative chemoradiation versus preoperative staging and chemoradiation in patients aged 70 years with resectable rectal cancer. In the postoperative chemoradiation strategy, patients undergo radical resection and receive postoperative chemoradiation. In the preopera-tive staging and chemoradiation strategy, patients with lo-cally advanced cancer receive preoperative chemoradiation and radical resection, whereas those with amenable localized tumors undergo local excision. The cohorts of patients were entered into a Markov model incorporating age-adjusted
Educational Role Student ♦ Teacher
Age Range above 22 year
Educational Use Research
Education Level UG and PG ♦ Career/Technical Study