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Author Kukkar, Deepak ♦ Kaur, Inderpreet ♦ Singh, Jagtar ♦ Bharadwaj, Lalit M.
Source CiteSeerX
Content type Text
File Format PDF
Subject Domain (in DDC) Computer science, information & general works ♦ Data processing & computer science
Subject Keyword Freeze Dried Microspheres ♦ Microvolcanic Eruption ♦ Liquid Nitrogen ♦ Field Emission Scanning Electron Microscope ♦ Present Work Report ♦ New Generation ♦ Aqueous Poly Vinyl Alcohol ♦ Aqueous Suspension ♦ Polymer Microspheres ♦ Convenient Methodology ♦ Caprolactone Microreactors ♦ Likewise Poly Caprolactone Microreactors ♦ Hollow Polymer Particle ♦ Micro-volcanic Rupture ♦ Unfunctionalized Quantum Dot ♦ Current Study ♦ Toluene Solution ♦ Tremendous Promise ♦ Hollow Particle ♦ Polystyrene Microcapsules ♦ Abstract Polymeric Microreactors ♦ Fluorescence Microscopy ♦ Polystyrene Latex Particle ♦ Drug Molecule ♦ Cancer Therapy
Abstract Abstract—Polymeric microreactors have emerged as a new generation of carriers that hold tremendous promise in the areas of cancer therapy, controlled delivery of drugs, for removal of pollutants etc. Present work reports a simple and convenient methodology for synthesis of polystyrene and poly caprolactone microreactors. An aqueous suspension of carboxylated (1µm) polystyrene latex particles was mixed with toluene solution followed by freezing with liquid nitrogen. Freezed particles were incubated at-20°C and characterized for formation of voids on the surface of polymer microspheres by Field Emission Scanning Electron Microscope. The hollow particles were then overnight incubated at 40ºC with unfunctionalized quantum dots (QDs) in 5:1 ratio. QDs Encapsulated polystyrene microcapsules were characterized by fluorescence microscopy. Likewise Poly ε-caprolactone microreactors were prepared by micro-volcanic rupture of freeze dried microspheres synthesized using emulsification of polymer with aqueous Poly vinyl alcohol and freezed with liquid nitrogen. Microreactors were examined with Field Emission Scanning Electron Microscope for size and morphology. Current study is an attempt to create hollow polymer particles which can be employed for microencapsulation of nanoparticles and drug molecules.
Educational Role Student ♦ Teacher
Age Range above 22 year
Educational Use Research
Education Level UG and PG ♦ Career/Technical Study