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Author Volkow, Nora D. ♦ Swanson, James M. ♦ Methylphenidate, Objective
Source CiteSeerX
Content type Text
File Format PDF
Subject Domain (in DDC) Computer science, information & general works ♦ Data processing & computer science
Subject Keyword Clinical Use ♦ Overview Variable ♦ Brain Imaging ♦ Abuse Liability ♦ Clinical Efficacy ♦ Clinical Literature ♦ Attention Deficit Hyperactivity Disorder ♦ Methyl-phenidate-induced Dopamine Increase ♦ Extracellufar Dopamine ♦ Therapeutic Effect ♦ Common Treatment
Abstract common treatment for attention deficit hyperactivity disorder (ADHD), increases extracellufar dopamine in the brain, which is associated with its reinforcing as well as its therapeutic effects. The authors evaluated variables that distinguish these two properties. Method: The brain imaging and clinical literatures were analyzed to identify vari-ables that contribute to the abuse liability as well as to the clinical efficacy of methyl-phenidate. Results: Four variables were identified. 1) Dose-there is a threshold for methyl-phenidate-induced dopamine increases
Educational Role Student ♦ Teacher
Age Range above 22 year
Educational Use Research
Education Level UG and PG ♦ Career/Technical Study