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Author Wiese, Jeff
Source CiteSeerX
Content type Text
File Format PDF
Subject Domain (in DDC) Computer science, information & general works ♦ Data processing & computer science
Subject Keyword Opuntia Ficus Indica ♦ Alcohol Hangover ♦ Urine Sample ♦ Alcohol Metabo-lism ♦ Identical Placebo ♦ Stressful Stimulus ♦ Alcohol Consumption ♦ Study Protocol ♦ Fol-lowing Morning ♦ Overall Well-being ♦ Inflammatory Response ♦ Body Weight ♦ Hangover Severity ♦ Young Adult Volunteer ♦ Alcohol Beverage ♦ Cross-over Trial
Abstract Background: The severity of the alcohol hangover may be related to inflammation induced by impurities in the alcohol beverage and byproducts of alcohol metabo-lism. An extract of the Opuntia ficus indica (OFI) plant diminishes the inflammatory response to stressful stimuli. Methods: In this double-blind, placebo-controlled, cross-over trial, 64 healthy, young adult volunteers were ran-domly assigned to receive OFI (1600 IU) and identical placebo, given 5 hours before alcohol consumption. Dur-ing 4 hours, subjects consumed up to 1.75 g of alcohol per kilogram of body weight. Hangover severity (9 symp-toms) and overall well-being were assessed on a scale (0-6), and blood and urine samples were obtained the fol-lowing morning. Two weeks later, the study protocol was repeated with OFI and placebo reversed.
Educational Role Student ♦ Teacher
Age Range above 22 year
Educational Use Research
Education Level UG and PG ♦ Career/Technical Study