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Author Liu, X. ♦ Brutlag, D. L. ♦ Liu, J. S.
Source CiteSeerX
Content type Text
File Format PDF
Language English
Subject Domain (in DDC) Computer science, information & general works ♦ Data processing & computer science
Subject Keyword Important Next Step ♦ Gene Expression ♦ Regulatory Signal ♦ Gene Expression Data Analysis Tool ♦ Substantial Insight ♦ Complete Genome ♦ Discovering Conserved Dna ♦ Upstream Region ♦ Last Ten Year ♦ Cultured Cell ♦ Gene Network ♦ Sequence Motif ♦ Environmental Change ♦ Transcriptional Regulatory Site ♦ Genomic Sequencing ♦ Regulatory Motif ♦ Genomic Scale ♦ Expression Pattern Group ♦ Dna Microarray Technology
Description Introduction Over the last ten years, genomic sequencing has started in over 600 organisms, and more than 50 complete genomes are publicly available. The DNA microarray technology permits the measurement of gene expression in cultured cells 1 . An increasing number of laboratories are using the combination of these two methods to study gene expression on a genomic scale. After all the genes from an organism are clustered based on their expression patterns 2 , an important next step is to examine the upstream region of genes in the same expression pattern group and look for sequence motifs. These motifs might be the regulatory signal (most likely a transcriptional regulatory site) that causes these genes to respond similarly to developmental or environmental changes. Information on expressions, regulatory motifs and functions provides substantial insight to the understanding of gene networks . The motivation of this research is to provide a gene expression data analysis tool t
Educational Role Student ♦ Teacher
Age Range above 22 year
Educational Use Research
Education Level UG and PG ♦ Career/Technical Study
Learning Resource Type Article
Publisher Date 2001-01-01
Journal Pac. Symp. Biocomput