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Author Wang, Lincong ♦ Mettu, Ramgopal R. ♦ Lilien, Ryan ♦ Bruce, R. ♦ Donald, All
Source CiteSeerX
Content type Text
File Format PDF
Language English
Subject Domain (in DDC) Computer science, information & general works ♦ Data processing & computer science
Subject Keyword Residual Dipolar Coupling ♦ Global Orientational Restraint ♦ Low-degree Polynomial Equation ♦ Novel Algorithm ♦ Exact Algorithm ♦ Consecutive Peptide Plane ♦ Solution Nmr ♦ Internuclear Bond Vector ♦ Bond Vector ♦ Protein Backbone Structure ♦ Depth-first Search ♦ Constant Time ♦ Nh Residual Dipolar Coupling ♦ Protein Backbone Structure Determination
Description We have developed a novel algorithm for protein backbone structure determination using global orientational restraints on internuclear bond vectors derived from residual dipolar couplings (RDCs) measured in solution NMR. The algorithm is a depth-first search (DFS) strategy that is built upon two low-degree polynomial equations for computing the backbone (φ, ψ) angles, exactly and in constant time, from two bond vectors in consecutive peptide planes. 1.
Educational Role Student ♦ Teacher
Age Range above 22 year
Educational Use Research
Education Level UG and PG ♦ Career/Technical Study
Learning Resource Type Article
Publisher Date 2003-01-01
Publisher Institution In IEEE Computer Society Bioinformatics Conference