|Author||Sonnenblick, T. Edmund H. ♦ Man, Unanesthetized ♦ Glick, Gerald ♦ Braunwald, Eugene|
|Subject Domain (in DDC)||Computer science, information & general works ♦ Data processing & computer science|
|Abstract||verse relationship between the force generated and the velocity of shortening constitutes one of the most fundamental mechanical properties of skeletal muscle (1). More recently it has been shown that a similar reciprocal relationship be-tween force and velocity also exists in the isolated cat papillary muscle (2-5). Moreover, at any given muscle length, various positive inotropic interventions, such as augmentation of heart rate (2, 3), administration of norepinephrine (3, 4), Ca++ (3), or digitalis (6), shift the force-velocity relation so that the velocity of shortening is greater at any given load and the maximal velocity of the unloaded muscle is increased. This type of shift in the force-velocity relation is interpreted to reflect an augmentation of the contractile state of the myocardium. The ability to alter the re-lationship between the force generated and the velocity of shortening in heart muscle is in con-trast with the relative stability of the force-velocity relation in skeletal muscle. Recently, studies on isolated human papillary muscle extended to man the concept that the force-velocity relation may be used to character-ize the basic contractile state of heart muscle (6). Fry, Griggs, and Greenfield (7) and Levine and Britman (8) have shown in open-chest dogs that the inverse relationship between force and in-stantaneous velocity is applicable to the intact canine ventricle. The objective of the present investigation was to determine whether or not the intact ventricle in conscious human subjects adheres to this basic law of muscular contraction that had been elucidated in various experimental|
|Educational Role||Student ♦ Teacher|
|Age Range||above 22 year|
|Education Level||UG and PG ♦ Career/Technical Study|
National Digital Library of India (NDLI) is a virtual repository of learning resources which is not just a repository with search/browse facilities but provides a host of services for the learner community. It is sponsored and mentored by Ministry of Education, Government of India, through its National Mission on Education through Information and Communication Technology (NMEICT). Filtered and federated searching is employed to facilitate focused searching so that learners can find the right resource with least effort and in minimum time. NDLI provides user group-specific services such as Examination Preparatory for School and College students and job aspirants. Services for Researchers and general learners are also provided. NDLI is designed to hold content of any language and provides interface support for 10 most widely used Indian languages. It is built to provide support for all academic levels including researchers and life-long learners, all disciplines, all popular forms of access devices and differently-abled learners. It is designed to enable people to learn and prepare from best practices from all over the world and to facilitate researchers to perform inter-linked exploration from multiple sources. It is developed, operated and maintained from Indian Institute of Technology Kharagpur.
NDLI is a conglomeration of freely available or institutionally contributed or donated or publisher managed contents. Almost all these contents are hosted and accessed from respective sources. The responsibility for authenticity, relevance, completeness, accuracy, reliability and suitability of these contents rests with the respective organization and NDLI has no responsibility or liability for these. Every effort is made to keep the NDLI portal up and running smoothly unless there are some unavoidable technical issues.
Ministry of Education, through its National Mission on Education through Information and Communication Technology (NMEICT), has sponsored and funded the National Digital Library of India (NDLI) project.
For any issue or feedback, please write to firstname.lastname@example.org