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Author Richard Bertram ♦ Jaeger, Dieter
Source CiteSeerX
Content type Text
File Format PDF
Subject Domain (in DDC) Computer science, information & general works ♦ Data processing & computer science
Subject Keyword Track Change ♦ Release Hormone ♦ Mathematical Modeling ♦ Endocrine Communication ♦ Single Cell ♦ Model-assisted Investigation ♦ Network Interaction ♦ Target Cell ♦ Substantial Morbidity ♦ Important Target ♦ Description Background ♦ Endocrine Gland ♦ Computer Simulation ♦ Adrenal Gland ♦ Endocrine System ♦ Endocrine System Refers ♦ Computational Work ♦ Endocrine Cell ♦ Several Endocrine Cell Type ♦ Synaptic Chemical Communication ♦ Hormone Act
Abstract The endocrine system refers to the cells and tissue that release hormones into the blood. Unlike synaptic chemical communication, which is localized to the target cell, endocrine communication is global. The hormones act on other endocrine glands such as the adrenal gland, ovaries, testes, and others, as well as on the heart, kidneys, muscle, and the brain. Mathematical modeling has been used to understand network interactions mediated by the endocrine system, as well as the effects of hormones on single cells. Detailed Description Background Like neurons, many endocrine cells are electrically excitable and release hormones through Ca 2+-mediated exocytosis (Stojilkovic et al. 2010). These have been the focus of mathematical modeling and computer simulation to better understand the mechanisms through which the cells operate. Several endocrine cell types are involved in diseases with substantial morbidity and mortality, making them an important target for model-assisted investigation. The most computational work to date has focused on the endocrine cells located within the
Educational Role Student ♦ Teacher
Age Range above 22 year
Educational Use Research
Education Level UG and PG ♦ Career/Technical Study