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Author Kuller, Lewis H. ♦ Pietropaolo, Massimo
Source CiteSeerX
Content type Text
File Format PDF
Subject Domain (in DDC) Computer science, information & general works ♦ Data processing & computer science
Subject Keyword Nutrition Examination Survey ♦ Third National Health ♦ Triethnic Adult Population ♦ Islet Cell Autoimmunity ♦ Gad65 Aa ♦ Nondiabetic Participant ♦ Ethnic Minority Adult Population ♦ High Prevalence ♦ U.s. Diabetic Population ♦ Auto-immune Diabetes ♦ Nhanes Iii ♦ Diabetic Participant ♦ Representative Ethnic Sample ♦ Non-hispanic Black ♦ 65-kda Isoform ♦ Humoral Islet Cell Autoimmunity ♦ Non-hispanic White
Abstract Markers of humoral islet cell autoimmunity, such as autoantibodies (AAs) against the 65-kDa isoform of GAD (GAD65), serve as determinants of risk for auto-immune diabetes. Despite the high prevalence of diabe-tes in U.S. racial and ethnic minority adult populations, little is known concerning the prevalence of GAD65 AA in these groups. We estimated the prevalence of GAD65 AA in 1,064 diabetic and 1,036 nondiabetic participants who were 40–90 years of age from the Third National Health and Nutrition Examination Survey (NHANES III), which provides a representative ethnic sample of the U.S. diabetic population. The prevalence of GAD65 AA was higher in diabetic participants compared with nondiabetic participants in non-Hispanic whites (n 920; 6.3 % vs. 2.0%; P 0.001) and non-Hispanic blacks
Educational Role Student ♦ Teacher
Age Range above 22 year
Educational Use Research
Education Level UG and PG ♦ Career/Technical Study