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Author Singh, Khumanthem Deepak ♦ Dass, Sandipan ♦ Yadav, Sunil
Source CiteSeerX
Content type Text
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Subject Domain (in DDC) Computer science, information & general works ♦ Data processing & computer science
Subject Keyword Ee Root ♦ Blood Glucose ♦ Serum Enzyme ♦ Diabetic Rat ♦ Ethanol Extract ♦ Solanum Surratense ♦ Serum Glutamate Pyruvate Transaminase ♦ Anti-diabetic Effect ♦ Diabetes Induced Rat ♦ Serum Lipid Profile Cholesterol ♦ Body Weight ♦ Single Dose ♦ Lipid Parameter ♦ Total Protein ♦ Alkaline Phosphatase ♦ Alloxan Monohydrate ♦ Albino Rat ♦ Wistar Albino Rat ♦ Significant Anti-diabetic Effect ♦ Serum Glutamate Oxaloacetate Transamines
Abstract ABSTRACT: The ethanol extract of Solanum surratense (EESS) (Family: Solanaceae) root was investigated for its anti-diabetic effect in Wistar Albino rats. Diabetes was induced in Albino rats by administration of single dose of Alloxan monohydrate (150mg/kg). The ethanol extract of Solanum surratense at the dose of 200mg/kg and 400mg/kg, p.o. was administered as single dose per day to diabetes induced rats for a period of 21 days. The effect of EESS root on body weight of the animals, blood glucose, serum lipid profile [cholesterol, triglycerides], serum enzymes[serum glutamate oxaloacetate transamines(SGOT), Serum glutamate pyruvate transaminases(SGPT), alkaline phosphatase(ALP)], total protein were measured in the diabetic rats. EESS root elicited significant (p< 0.01) reductions of blood glucose, lipid parameters and serum enzymes and significant (p<0.01) reductions of blood glucose. From the above result, it is concluded that EESS root possesses significant anti-diabetic effects in Alloxan induced diabetic rats.
Educational Role Student ♦ Teacher
Age Range above 22 year
Educational Use Research
Education Level UG and PG ♦ Career/Technical Study
Learning Resource Type Article